DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG10321 and Zbtb32

DIOPT Version :9

Sequence 1:NP_001261124.1 Gene:CG10321 / 37464 FlyBaseID:FBgn0034643 Length:855 Species:Drosophila melanogaster
Sequence 2:NP_067372.2 Gene:Zbtb32 / 58206 MGIID:1891838 Length:465 Species:Mus musculus


Alignment Length:426 Identity:89/426 - (20%)
Similarity:138/426 - (32%) Gaps:130/426 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly   327 LGDAD-------VQLLEDGCEVEDEELEDVYEQLDSKADHSFETIVLDDDQQQDFLKDHHEHHQV 384
            |||.:       ||.||:.|:               :|...     .|:|:....||.|.:    
Mouse    90 LGDLEEAAKALGVQALEEACQ---------------RAQKG-----KDEDELDPGLKRHQQ---- 130

  Fly   385 MINEDLTQSESQDHEYFDDLDQQQAMDEIEDEEEQMKPEED-------QDTFIIEEIQLEDDEML 442
              :||..:...:.               :....|:.|||:|       |:.....:...|..||.
Mouse   131 --SEDFMRGSERG---------------LGSPGEKQKPEKDFRSNGREQEMSHKHKAPGERPEMA 178

  Fly   443 DDP---DGEEIDQDCE-YIGEEQDPHLSGDVDDDLEYSIMEPPDGETSVDIDQAFMDSEQSHHQQ 503
            ...   ..||:.:..| :.|.|:.  |.|..|.      :.||....:..|.:.:. :|.....:
Mouse   179 GATRMMSSEEVMRGIESHKGSEES--LRGCPDP------LSPPGSLLTSLIPRPWW-AEVPRLGE 234

  Fly   504 HQEEMQSISL--ENAVVEFSQATTTTEA-LVGP-------TMT----------VSSASPTPKRAK 548
            .|..:.||.|  ......||.:|..|.| .|.|       |:.          ::|:||||    
Mouse   235 GQSALWSILLWPSRYGAPFSHSTPITAAWQVRPQDQRIPLTLNHSKALWSQNQLASSSPTP---- 295

  Fly   549 RSNHQIPAGV-TLEPCDHQPPAAGSTTSSKLAAANSRQLVQTASVIAAAGADDNYEIDANLVTEF 612
               ...|.|. ||.|...:....|.|.:.....:..|.|                    |..:  
Mouse   296 ---GSFPQGTETLSPWQIETSGQGFTGTLATCVSQERTL--------------------NCPS-- 335

  Fly   613 IRQH---TSPLGSGRYICHLCSTEFRQFKGLQNHMHSHTNWIRANCKKQPQCQICLKSFKGPGML 674
             .||   .||..|..|.|.:|...|.....::.|...||.      :|...|.:|.:..:....:
Mouse   336 -HQHPPLPSPARSRPYSCSVCGKRFSLKHQMETHYRVHTG------EKPFSCSLCPQRSRDFSAM 393

  Fly   675 RMHMKTHDAESSTPMCTICNRTFKSKAILYRHRQTH 710
            ..|::||.|  :...|.:|.....|.|.:..|.:.|
Mouse   394 TKHLRTHGA--APYRCPLCRAGCPSLASMQAHMRGH 427

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG10321NP_001261124.1 zf-AD 12..80 CDD:214871
ASF1_hist_chap <405..516 CDD:304562 25/123 (20%)
C2H2 Zn finger 627..647 CDD:275368 4/19 (21%)
C2H2 Zn finger 661..681 CDD:275368 3/19 (16%)
C2H2 Zn finger 690..710 CDD:275368 5/19 (26%)
C2H2 Zn finger 717..740 CDD:275368
C2H2 Zn finger 750..767 CDD:275368
Zbtb32NP_067372.2 BTB_POZ 13..114 CDD:365784 9/38 (24%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 111..179 17/93 (18%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 285..310 10/31 (32%)
zf-C2H2 350..372 CDD:333835 5/21 (24%)
C2H2 Zn finger 352..372 CDD:275368 4/19 (21%)
zf-H2C2_2 365..386 CDD:372612 6/26 (23%)
C2H2 Zn finger 380..400 CDD:275368 3/19 (16%)
C2H2 Zn finger 407..427 CDD:275368 5/19 (26%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR24399
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.100

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