DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10321 and znf1007

DIOPT Version :9

Sequence 1:	NP_001261124.1	Gene:	CG10321 / 37464	FlyBaseID:	FBgn0034643	Length:	855	Species:	Drosophila melanogaster
Sequence 2:	XP_001921925.4	Gene:	znf1007 / 553302	ZFINID:	ZDB-GENE-131120-139	Length:	2186	Species:	Danio rerio

Alignment Length:	436	Identity:	98/436 - (22%)
Similarity:	153/436 - (35%)	Gaps:	117/436 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   380 EHHQVMINEDLTQSESQDHEYFDDLDQQQAMDEIEDEEEQMKPEEDQDTFIIEEIQLEDDEMLDD 444
            |..:.|:.|:..:.:.:|.|...||    .:.::||:|:.||    .|..:..|..:||:..:..
Zfish     6 EESEDMMTEETLEIKQEDAEEEADL----IVMKLEDDEKSMK----FDHQVGLETHIEDNSHICS 62

  Fly   445 PDGEEIDQDCEYIGEEQDPHLSGDVDDDLEYSIMEPPDGETSVDIDQAFMDSEQSH--------- 500
            ..||..:     :.|..|.|::       .:|...|   .|.:...::|....:.|
Zfish    63 ECGERFE-----LKESLDAHMN-------IHSRAMP---YTCLQCGKSFTTEARFHTHLSIHSGI 112

  Fly   501 -----------------HQQHQEEMQSISLENAVVEFSQATTTTEAL-----VGPTMTVSSASPT 543
                             .:.|.:.|.:.....|.........|::.|     ..|.|...:....
Zfish   113 KPFTCQYCGKGFRNGRCFKLHLKRMHAREKPYACQYCGTCFNTSKKLKAHVKTHPEMKTCACELC 177

  Fly   544 PKRAKRSN---H-QIPAGVTLEPCDHQPPAAGSTTSSKLAAANSRQLVQTASVIAAAGADDNYEI 604
            .||..|.:   | :|..|.....|.:    .|.:.|.|.:..|
Zfish   178 GKRLSRKSLKKHMRIHTGEKPYSCSY----CGMSFSFKTSLKN---------------------- 216

  Fly   605 DANLVTEFIRQHTSPLGSGRYICHLCSTEFRQFKGLQNHMHSHTNWIRANCKKQPQCQICLKSFK 669
                   .|..||   |...|.|.:|...|.:...|:.||.||:|      ::...|..|.||||
Zfish   217 -------HIVNHT---GEKPYSCSICGKSFIEQGRLKIHMISHSN------ERPYSCSQCGKSFK 265

  Fly   670 GPGMLRMHMKTHDAESSTPMCTICNRTFKSKAILYRHRQTH-QQRAYCCGVANCRKNFSSA---- 729
            ....:|:||||| .......|:.|.|:|.....|..|.:.| .:|.|.|  :.|.|.|.|.
Zfish   266 SQRCVRLHMKTH-TNKKPHSCSQCGRSFNKLGDLNAHIKAHSDERPYSC--SKCGKGFISQTRLN 327

  Fly   730 VNLKWHVERKHPEVVDPLFKCGECGSLYDNVDSLQLHVESTDHSAE 775
            |::|:|...|      |.| |.|||..:...|.:..|:..  |:.|
Zfish   328 VHMKFHTAEK------PFF-CSECGRNFKTQDCVNRHMHI--HTVE 364

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10321	NP_001261124.1	zf-AD	12..80	CDD:214871
		ASF1_hist_chap	<405..516	CDD:304562	21/136 (15%)
		C2H2 Zn finger	627..647	CDD:275368	6/19 (32%)
		C2H2 Zn finger	661..681	CDD:275368	10/19 (53%)
		C2H2 Zn finger	690..710	CDD:275368	6/19 (32%)
		C2H2 Zn finger	717..740	CDD:275368	8/26 (31%)
		C2H2 Zn finger	750..767	CDD:275368	5/16 (31%)
znf1007	XP_001921925.4	C2H2 Zn finger	61..81	CDD:275368	5/31 (16%)
		C2H2 Zn finger	89..109	CDD:275368	2/19 (11%)
		C2H2 Zn finger	117..138	CDD:275368	1/20 (5%)
		COG5048	142..525	CDD:227381	70/277 (25%)
		C2H2 Zn finger	146..166	CDD:275368	2/19 (11%)
		C2H2 Zn finger	174..193	CDD:275368	4/18 (22%)
		zf-H2C2_2	185..209	CDD:290200	5/27 (19%)
		C2H2 Zn finger	201..221	CDD:275368	6/52 (12%)
		C2H2 Zn finger	229..249	CDD:275368	6/19 (32%)
		C2H2 Zn finger	257..277	CDD:275368	10/19 (53%)
		C2H2 Zn finger	285..305	CDD:275368	6/19 (32%)
		C2H2 Zn finger	313..333	CDD:275368	7/21 (33%)
		C2H2 Zn finger	341..361	CDD:275368	6/21 (29%)
		C2H2 Zn finger	369..389	CDD:275368
		C2H2 Zn finger	397..417	CDD:275368
		C2H2 Zn finger	453..473	CDD:275368
		C2H2 Zn finger	481..501	CDD:275368
		COG5048	504..953	CDD:227381
		C2H2 Zn finger	509..529	CDD:275368
		C2H2 Zn finger	537..557	CDD:275368
		C2H2 Zn finger	574..594	CDD:275368
		C2H2 Zn finger	611..631	CDD:275368
		C2H2 Zn finger	639..659	CDD:275368
		C2H2 Zn finger	676..696	CDD:275368
		C2H2 Zn finger	704..724	CDD:275368
		C2H2 Zn finger	741..761	CDD:275368
		C2H2 Zn finger	769..790	CDD:275368
		C2H2 Zn finger	807..827	CDD:275368
		C2H2 Zn finger	836..855	CDD:275368
		C2H2 Zn finger	876..892	CDD:275368
		C2H2 Zn finger	900..920	CDD:275368
		COG5048	933..1410	CDD:227381
		C2H2 Zn finger	937..957	CDD:275368
		C2H2 Zn finger	965..985	CDD:275368
		C2H2 Zn finger	1002..1022	CDD:275368
		C2H2 Zn finger	1030..1051	CDD:275368
		C2H2 Zn finger	1068..1088	CDD:275368
		C2H2 Zn finger	1096..1116	CDD:275368
		C2H2 Zn finger	1133..1153	CDD:275368
		C2H2 Zn finger	1170..1190	CDD:275368
		C2H2 Zn finger	1211..1227	CDD:275368
		C2H2 Zn finger	1235..1255	CDD:275368
		C2H2 Zn finger	1272..1292	CDD:275368
		C2H2 Zn finger	1300..1320	CDD:275368
		C2H2 Zn finger	1337..1357	CDD:275368
		C2H2 Zn finger	1378..1394	CDD:275368
		C2H2 Zn finger	1402..1422	CDD:275368
		COG5048	1435..1830	CDD:227381
		C2H2 Zn finger	1439..1459	CDD:275368
		C2H2 Zn finger	1467..1487	CDD:275368
		C2H2 Zn finger	1504..1524	CDD:275368
		C2H2 Zn finger	1532..1552	CDD:275368
		C2H2 Zn finger	1569..1589	CDD:275368
		C2H2 Zn finger	1597..1617	CDD:275368
		C2H2 Zn finger	1634..1654	CDD:275368
		C2H2 Zn finger	1671..1691	CDD:275368
		C2H2 Zn finger	1708..1728	CDD:275368
		C2H2 Zn finger	1736..1756	CDD:275368
		COG5048	1769..2180	CDD:227381
		C2H2 Zn finger	1773..1793	CDD:275368
		C2H2 Zn finger	1801..1821	CDD:275368
		C2H2 Zn finger	1838..1858	CDD:275368
		C2H2 Zn finger	1875..1895	CDD:275368
		C2H2 Zn finger	1912..1932	CDD:275368
C2H2 Zn finger	1940..1961	CDD:275368
C2H2 Zn finger	1969..1989	CDD:275368
C2H2 Zn finger	1997..2016	CDD:275368
zf-H2C2_2	2008..2033	CDD:290200
C2H2 Zn finger	2024..2044	CDD:275368
C2H2 Zn finger	2052..2071	CDD:275368
C2H2 Zn finger	2080..2100	CDD:275368
C2H2 Zn finger	2112..2128	CDD:275368
C2H2 Zn finger	2136..2156	CDD:275368
C2H2 Zn finger	2164..2184	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24399
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.100