DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10321 and zbtb2

DIOPT Version :9

Sequence 1:	NP_001261124.1	Gene:	CG10321 / 37464	FlyBaseID:	FBgn0034643	Length:	855	Species:	Drosophila melanogaster
Sequence 2:	NP_001016668.1	Gene:	zbtb2 / 549422	XenbaseID:	XB-GENE-977864	Length:	514	Species:	Xenopus tropicalis

Alignment Length:	381	Identity:	75/381 - (19%)
Similarity:	119/381 - (31%)	Gaps:	123/381 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   509 QSISLENAVVEFSQATTTTEALVGPTMTVSSASPTPKRAKRSNHQIPAGVTLE-------PCDHQ 566
            |..:.||  |:.||..:.........:|.|.....|...:.|:..:|...::|       |.|.|
Frog   168 QDTTSEN--VQISQLPSALPTANRTNLTFSETVHAPLSPEASSSVLPTATSVEENSMEESPTDEQ 230

  Fly   567 PPAAGSTTSSKLAAANSRQLVQTASVIAAAGADDNYEIDANLVTEFIRQHTSPLGSGRYICHLCS 631
                    ::.|..|:.:     .|::...|:...|                      |.||||.
Frog   231 --------NTSLTIAHVK-----PSIMKRNGSFPKY----------------------YACHLCG 260

  Fly   632 TEFRQFKGLQNHMHSHTNWIRANCKKQPQCQICLKSF--KGPGMLRMHMKTHDA----------- 683
            ..|.....|:.|:..||....::...|.:..|. .||  .|..:.:..|:|.:|
Frog   261 RRFNLRSSLREHLQLHTGIPFSSAAGQTETSIS-PSFCNNGADLGKESMETTEAGIISDSDMPQI 324

  Fly   684 ----------ESSTP-------------------------MCTICNRTFKSKAILYRHRQTHQQR 713
                      ::.||                         .|:||.|.|..|:....|...|..:
Frog   325 SDSPIIDGQQQAETPPPTDIADIDNLEQADQEREVKRRKYECSICGRKFIQKSHWREHMYIHTGK 389

  Fly   714 AYCCGVANCRKNFSSAVNLKWHVERKHPEVVDPLFKCGECGSLYDNVDSLQLHVESTDHSAE--- 775
            .:.|  :.|.|:|..|.....||             |.:....|..||...|.:.|.|..::
Frog   390 PFKC--STCDKSFCRANQAARHV-------------CLKSSDTYTVVDKQTLELCSFDEGSQMDN 439

  Fly   776 --VQISGQ------DDAFSGAVSIVSNGTTDMSN---MMATGQGTTLAGGTGDTHA 820
              ||.:.:      |..||....:|.: |....|   .....:|..|...:||:.|
Frog   440 MLVQTNKRYKCNVCDKTFSTPNEVVKH-TCQSQNSDVFALEEEGKPLLLSSGDSEA 494

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10321	NP_001261124.1	zf-AD	12..80	CDD:214871
		ASF1_hist_chap	<405..516	CDD:304562	2/6 (33%)
		C2H2 Zn finger	627..647	CDD:275368	7/19 (37%)
		C2H2 Zn finger	661..681	CDD:275368	5/21 (24%)
		C2H2 Zn finger	690..710	CDD:275368	7/19 (37%)
		C2H2 Zn finger	717..740	CDD:275368	7/22 (32%)
		C2H2 Zn finger	750..767	CDD:275368	5/16 (31%)
zbtb2	NP_001016668.1	BTB_POZ_ZBTB2	3..117	CDD:349502
		ZnF_C2H2	254..276	CDD:197676	8/21 (38%)
		C2H2 Zn finger	256..276	CDD:275368	7/19 (37%)
		zf-C2H2	364..386	CDD:333835	7/21 (33%)
		C2H2 Zn finger	366..386	CDD:275368	7/19 (37%)
		zf-H2C2_2	378..400	CDD:372612	5/23 (22%)
		C2H2 Zn finger	393..443	CDD:275368	14/64 (22%)
		C2H2 Zn finger	450..466	CDD:275368	4/15 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24399
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010