DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10321 and Zif

DIOPT Version :9

Sequence 1:	NP_001261124.1	Gene:	CG10321 / 37464	FlyBaseID:	FBgn0034643	Length:	855	Species:	Drosophila melanogaster
Sequence 2:	NP_001189188.1	Gene:	Zif / 40795	FlyBaseID:	FBgn0037446	Length:	388	Species:	Drosophila melanogaster

Alignment Length:	419	Identity:	86/419 - (20%)
Similarity:	155/419 - (36%)	Gaps:	95/419 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   390 LTQSESQDHEYFDDLDQQQAMDEIEDEEEQMKPEEDQDTFIIEEIQLEDDEMLDDPDG------- 447
            |.|||           :.|.:|||.:|.|:...|.......:....|.|.|.:  |||
  Fly    14 LAQSE-----------RLQRLDEIREEGEESPNEMLIQLLGVSYSNLNDREHI--PDGICKSCKV 65

  Fly   448 ----------------EEIDQDCEYIGEEQDPHLSGDVDDDLEYSIMEPPDG-ETSVDIDQAFMD 495
                            .||::.|..:|          :.|:.:..:::..|| :...|.:...::
  Fly    66 ELNMAYQFREKALRKQMEIEEYCRELG----------LLDESDVMMIKEEDGSQQQCDEEMYILE 120

  Fly   496 SEQSHHQQHQEEMQSISLENAVVEFSQATTTTEALVGPTMTVSSASPTPKRAKRSNHQIPAGVTL 560
            ...:..::|||       |....|:.:..|                        |:.|...|.|:
  Fly   121 ETTTGEEEHQE-------EKGHEEYLEVDT------------------------SDQQECIGDTI 154

  Fly   561 EPCDHQPPAAGSTTSSKLAAANSRQLVQTAS--VIAAAGADDNYEIDANLVTEFIRQHTSPLGS- 622
            |..:.......::..:::...:.:|..:|.|  :.....|..:.:.....|...:...|:..|:
  Fly   155 EYLEDNYTIEMNSDQTEIVLESEKQYEETPSQQLALQEAAKASLKARRGRVRRGLNSLTTSDGTE 219

  Fly   623 -GRYICHLCSTEFRQFKGLQNHMHSHTNWIRANCKKQPQCQICLKSFKGPGMLRMHMKTHDAESS 686
             |.|||.:|...:.:...:..|...|.    ..|  |..|::|...|:....||.||.:|.. |.
  Fly   220 KGGYICDVCGNFYEKRGRMMEHRRRHD----GIC--QYACELCDAKFQVREQLRKHMYSHTG-SK 277

  Fly   687 TPMCTICNRTFKSKAILYRHRQTHQQ-RAYCCGVANCRKNFSSAVNLKWHVERKHPEVVDPLFKC 750
            ...|:.|:|.|..:::|..|...|:. :.|.|.|  |.|.|:.|.:|..| |..|.::  .|::|
  Fly   278 PYKCSFCSRQFFYESVLKSHENVHRGIKPYVCKV--CDKAFAYAHSLTKH-ELIHSDI--KLYRC 337

  Fly   751 GECGSLYDNVDSLQLHVESTDHSAEVQIS 779
            ..|...:..:..::.|.|:..|...|.::
  Fly   338 DYCNKDFRLLHHMRQHEETKLHQNAVMLA 366

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10321	NP_001261124.1	zf-AD	12..80	CDD:214871
		ASF1_hist_chap	<405..516	CDD:304562	25/134 (19%)
		C2H2 Zn finger	627..647	CDD:275368	3/19 (16%)
		C2H2 Zn finger	661..681	CDD:275368	7/19 (37%)
		C2H2 Zn finger	690..710	CDD:275368	6/19 (32%)
		C2H2 Zn finger	717..740	CDD:275368	9/22 (41%)
		C2H2 Zn finger	750..767	CDD:275368	2/16 (13%)
Zif	NP_001189188.1	zf-AD	9..87	CDD:285071	19/85 (22%)
		C2H2 Zn finger	225..245	CDD:275368	3/19 (16%)
		COG5048	<250..369	CDD:227381	35/123 (28%)
		C2H2 Zn finger	253..273	CDD:275368	7/19 (37%)
		zf-H2C2_2	266..288	CDD:290200	9/22 (41%)
		C2H2 Zn finger	281..301	CDD:275368	6/19 (32%)
		zf-H2C2_2	294..318	CDD:290200	9/25 (36%)
		C2H2 Zn finger	309..329	CDD:275368	9/22 (41%)
		C2H2 Zn finger	337..353	CDD:275368	2/15 (13%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	0	0.000