DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG10321 and Zbtb2

DIOPT Version :9

Sequence 1:NP_001261124.1 Gene:CG10321 / 37464 FlyBaseID:FBgn0034643 Length:855 Species:Drosophila melanogaster
Sequence 2:NP_001028638.2 Gene:Zbtb2 / 381990 MGIID:2685949 Length:514 Species:Mus musculus


Alignment Length:427 Identity:81/427 - (18%)
Similarity:126/427 - (29%) Gaps:140/427 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly   489 IDQAFMDSEQSHHQQHQEEMQSISLENAVVEFSQATTTTEALVGPTMTVSSASPTPKRAKRSNHQ 553
            |.:|.:.|:.|.....|....:.||....:...|....|:..:||...  ...|.|:.::.:...
Mouse   108 IQEASLASQGSFSHPEQVFPLASSLYGIQIADHQLRQATKMNLGPEKL--GREPRPQASRMNQEP 170

  Fly   554 IPAGVTLEPCDHQPPAAGSTTSSKLAAAN--------------SRQLVQTASVIAAAGADDNYEI 604
            :|....|           |..:|.||..|              |.:||.|.......|.:.|.|.
Mouse   171 VPETSQL-----------SQLTSNLAQVNRTNITPEDPLQTSLSPELVSTPVPPPPPGEETNLEA 224

  Fly   605 DAN--LVTEFIRQHTSPLGSGR-------YICHLCSTEFRQFKGLQNHMHSHTNWIRANCKKQPQ 660
            .::  ..:.....|..|....|       |.||||...|.....|:.|:..||.           
Mouse   225 SSSDEQPSSLTIAHVKPSIMKRNGSFPKYYACHLCGRRFTLRSSLREHLQIHTG----------- 278

  Fly   661 CQICLKSFKGP---------------------------GMLRMHMKTH---------DAESSTP- 688
                :....||                           ||:......|         ..:|.|| 
Mouse   279 ----VPFTAGPPGEGRGPLSLCSNAADLGKDALEVPEAGMISDSELQHISDSPIIDGQQQSETPP 339

  Fly   689 ------------------------MCTICNRTFKSKAILYRHRQTHQQRAYCCGVANCRKNFSSA 729
                                    .||||.|.|..|:....|...|..:.:.|  :.|.|:|..|
Mouse   340 PSDIADIDNLEQADQEREVKRRKYECTICGRKFIQKSHWREHMYIHTGKPFKC--STCDKSFCRA 402

  Fly   730 VNLKWHVERKHPEVVDPLFKC-GECGSLYDNVDSLQLHVESTDHSAE-----VQISGQ------D 782
            .....||             | .:....|..||...|.:.:.:..::     ||.:..      |
Mouse   403 NQAARHV-------------CLNQSIDTYTMVDKQTLELCTFEEGSQMDNMLVQANKPYKCNLCD 454

  Fly   783 DAFSGAVSIVSNGTTDM-SNMMATGQGTTLAGGTGDT 818
            ..||....:|.:...:. |::.|..:|.::..|:||:
Mouse   455 KTFSTPNEVVKHSCQNQNSDVFALDEGRSVLLGSGDS 491

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG10321NP_001261124.1 zf-AD 12..80 CDD:214871
ASF1_hist_chap <405..516 CDD:304562 7/26 (27%)
C2H2 Zn finger 627..647 CDD:275368 7/19 (37%)
C2H2 Zn finger 661..681 CDD:275368 4/46 (9%)
C2H2 Zn finger 690..710 CDD:275368 8/19 (42%)
C2H2 Zn finger 717..740 CDD:275368 7/22 (32%)
C2H2 Zn finger 750..767 CDD:275368 5/17 (29%)
Zbtb2NP_001028638.2 BTB 14..>84 CDD:306997
zf-C2H2 254..276 CDD:306579 8/21 (38%)
C2H2 Zn finger 256..276 CDD:275368 7/19 (37%)
zf-C2H2 363..385 CDD:306579 8/21 (38%)
C2H2 Zn finger 365..385 CDD:275368 8/19 (42%)
zf-H2C2_2 377..399 CDD:316026 5/23 (22%)
C2H2 Zn finger 392..416 CDD:275368 8/38 (21%)
C2H2 Zn finger 450..466 CDD:275368 4/15 (27%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR24399
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.100

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