DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10321 and Bcl6

DIOPT Version :9

Sequence 1:	NP_001261124.1	Gene:	CG10321 / 37464	FlyBaseID:	FBgn0034643	Length:	855	Species:	Drosophila melanogaster
Sequence 2:	NP_001100554.1	Gene:	Bcl6 / 303836	RGDID:	1309345	Length:	707	Species:	Rattus norvegicus

Alignment Length:	316	Identity:	75/316 - (23%)
Similarity:	114/316 - (36%)	Gaps:	45/316 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   479 EPPDGETSVDIDQAFMDSEQSHHQQHQEEMQSISLENAVVEFSQATTTTEALVG-PTMTVSSASP 542
            :||....::|:..   .::.|...:.....|:..|.|.|         ..:|.| |..:..|.||
  Rat   416 QPPMEPANLDLQS---PTKLSASGEDSTIPQASRLNNIV---------NRSLAGSPRSSSESHSP 468

  Fly   543 T---PKRAKRSNHQIPAGVTLEPCDHQPPAAGSTTSSKLAAANSRQLVQTASVIAAAGADDNYEI 604
            .   |.:......|.|...  |.|.|   .||.|...::....|    :.:......||....|.
  Rat   469 LYMHPPKCTSCGSQSPQHT--EMCLH---TAGPTFPEEMGETQS----EYSDSSCENGAFFCNEC 524

  Fly   605 DANLVTE-FIRQHTSPLGSGR-YICHLCSTEFRQFKGLQNHMHSHTNWIRANCKKQPQCQICLKS 667
            |.....| .:::||....|.: |.|..|...||....|.:|...||.      :|..:|.||...
  Rat   525 DCRFSEEASLKRHTLQTHSDKPYKCDRCQASFRYKGNLASHKTVHTG------EKPYRCNICGAQ 583

  Fly   668 FKGPGMLRMHMKTHDAESSTPMCTICNRTFKSKAILYRHRQTHQ-QRAYCCGVANCRKNFSSAVN 731
            |..|..|:.|.:.|..|... .|..|...|...|.|..|...|. ::.|.|.:  |...|.....
  Rat   584 FNRPANLKTHTRIHSGEKPY-KCETCGARFVQVAHLRAHVLIHTGEKPYPCEI--CGTRFRHLQT 645

  Fly   732 LKWHVERKHPEVVDPLFKCGECGSLYDNVDSLQLHVES-----TDHSAEVQISGQD 782
            ||.|: |.|  ..:..:.|.:|...:.:...|:||:..     |:...:.::|..|
  Rat   646 LKSHL-RIH--TGEKPYHCEKCNLHFRHKSQLRLHLRQKHGAITNTKVQYRVSAAD 698

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10321	NP_001261124.1	zf-AD	12..80	CDD:214871
		ASF1_hist_chap	<405..516	CDD:304562	6/36 (17%)
		C2H2 Zn finger	627..647	CDD:275368	6/19 (32%)
		C2H2 Zn finger	661..681	CDD:275368	7/19 (37%)
		C2H2 Zn finger	690..710	CDD:275368	6/19 (32%)
		C2H2 Zn finger	717..740	CDD:275368	7/22 (32%)
		C2H2 Zn finger	750..767	CDD:275368	4/16 (25%)
Bcl6	NP_001100554.1	BTB_POZ_ZBTB27_BCL6	8..125	CDD:349640
		PHA03247	<173..427	CDD:223021	3/10 (30%)
		C2H2 Zn finger	521..542	CDD:275368	5/20 (25%)
		C2H2 Zn finger	549..569	CDD:275368	6/19 (32%)
		zf-H2C2_2	561..586	CDD:404364	9/30 (30%)
		C2H2 Zn finger	577..597	CDD:275368	7/19 (37%)
		zf-H2C2_2	589..614	CDD:404364	7/25 (28%)
		C2H2 Zn finger	605..625	CDD:275368	6/19 (32%)
		zf-H2C2_2	617..642	CDD:404364	7/26 (27%)
		C2H2 Zn finger	633..653	CDD:275368	7/22 (32%)
		zf-H2C2_2	646..670	CDD:404364	7/26 (27%)
		C2H2 Zn finger	661..679	CDD:275368	5/17 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24399
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100