DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10321 and Zbtb20

DIOPT Version :9

Sequence 1:	NP_001261124.1	Gene:	CG10321 / 37464	FlyBaseID:	FBgn0034643	Length:	855	Species:	Drosophila melanogaster
Sequence 2:	NP_001099350.2	Gene:	Zbtb20 / 288105	RGDID:	1560387	Length:	741	Species:	Rattus norvegicus

Alignment Length:	639	Identity:	136/639 - (21%)
Similarity:	215/639 - (33%)	Gaps:	203/639 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   270 LLQTPNGQTLQIVQQPNGTQTLQLVQLVPQRSLAPTGVTTVTTTTNATDMGQHVGASLGDADVQL 334
            :|:....:.|||:   .....||:..::.:        .|...:.|..|:...:..|..|.....
  Rat   162 VLRVSQSEALQIL---TAASILQIKTVIDE--------CTRIVSQNVGDVFPGIQDSGQDTPRGT 215

  Fly   335 LEDGCEVEDEELEDVYEQLDSKADHSFETI--------VLDDDQQQDF----LKDHHE------- 380
            .|.|...:..:.|..|  |.|...||.:.|        :.:...::.|    :..|||
  Rat   216 PESGTSGQSSDTESGY--LQSHPQHSVDRIYSALYACSMQNGSGERSFYSGAVVSHHETALGLPR 278

  Fly   381 -HHQVMINED------LTQSESQDHEYFDDLDQ-------------QQAMDEIEDEEEQMKPEED 425
             ||.    ||      :.:...|...|.....:             |..:..|..::|.   |:|
  Rat   279 DHHM----EDPSWITRIHERSQQMERYLSTTPETTHCRKQPRPVRIQTLVGNIHIKQEM---EDD 336

  Fly   426 QDTFIIEEIQL----EDDEMLDDPDGEEIDQDCEYIGEEQDPHLSGD-VDDDLEYSIMEPPD--- 482
            .|.:..:.:|:    |.:|..:|.|..|        |.|.:|  .|: .|..:..||...||
  Rat   337 YDYYGQQRVQILERNESEECTEDTDQAE--------GTESEP--KGESFDSGVSSSIGTEPDSVE 391

  Fly   483 -----GET------SVDIDQAFMDSEQSHHQQHQ--------EEMQSISLENAVVEFS------- 521
                 |.|      :...:||.....:|..|.:|        |....:.::|.|:..|
  Rat   392 QQFGAGATREGQVEAAQPEQAAEAPAESSAQPNQLETGASSPERSTEVEMDNTVITVSNSSDKGV 456

  Fly   522 -----------QATTTTEALVGPTMTVSS--------ASPTPKRAKRSNHQIPAGVTLEPCDHQP 567
                       |...:|:..:..|.|::|        .|.|.......|..:||..|.:|....|
  Rat   457 LQQPSVNTSIGQPLPSTQLYLRQTETLTSNLRMPLTLTSNTQVIGTAGNTYLPALFTTQPAGSGP 521

  Fly   568 ---------PAAG-------------STTSSKLAAANSRQLVQTASVIAAAGADDNYEIDANLVT 610
                     |..|             ||.:::|.|  .:.|..:||...|:|..|.
  Rat   522 KPFLFSLPQPLTGQQTQFVTVSQPGLSTFTAQLPA--PQPLASSASHSTASGQGDK--------- 575

  Fly   611 EFIRQHTSPLGSGRYICHLCSTEFRQFKGLQNHMHSHTNWIRANCKKQPQCQICLKSFKGPGMLR 675
                   .|     |.|.||:..|...:....||..||.      :|..||.||.:||.....|.
  Rat   576 -------KP-----YECTLCNKTFTAKQNYVKHMFVHTG------EKPHQCSICWRSFSLKDYLI 622

  Fly   676 MHMKTHDAESSTPMCTICNRTFKSKAILYRHRQTHQ-QRAYCCGVANCRKNFSSAVNLKWHV--- 736
            .||.||....:. .|:|||:.|..|:.|..|.:.|: :::|.|.:  |:|.||....|:.||
  Rat   623 KHMVTHTGVRAY-QCSICNKRFTQKSSLNVHMRLHRGEKSYECYI--CKKKFSHKTLLERHVALH 684

  Fly   737 ---------------ERKHPEVV----DPLFKCGECGSLYDNV----DSLQLHV 767
                           ....|.||    ...:.|..|.:.:|.:    |.:::||
  Rat   685 SASNGTPPAGTPPGARAGPPGVVACTEGTTYVCSVCPAKFDQIEQFNDHMRMHV 738

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10321	NP_001261124.1	zf-AD	12..80	CDD:214871
		ASF1_hist_chap	<405..516	CDD:304562	29/150 (19%)
		C2H2 Zn finger	627..647	CDD:275368	6/19 (32%)
		C2H2 Zn finger	661..681	CDD:275368	8/19 (42%)
		C2H2 Zn finger	690..710	CDD:275368	8/19 (42%)
		C2H2 Zn finger	717..740	CDD:275368	8/40 (20%)
		C2H2 Zn finger	750..767	CDD:275368	4/20 (20%)
Zbtb20	NP_001099350.2	BTB_POZ_ZBTB20_DPZF	79..195	CDD:349517	7/43 (16%)
		zf-C2H2	578..600	CDD:395048	7/21 (33%)
		C2H2 Zn finger	580..600	CDD:275368	6/19 (32%)
		SUF4-like	608..>657	CDD:411020	18/49 (37%)
		C2H2 Zn finger	608..629	CDD:411020	9/20 (45%)
		C2H2 Zn finger	608..628	CDD:275368	8/19 (42%)
		zf-C2H2	634..656	CDD:395048	8/22 (36%)
		C2H2 Zn finger	636..656	CDD:411020	8/19 (42%)
		C2H2 Zn finger	636..656	CDD:275368	8/19 (42%)
		zf-H2C2_2	648..673	CDD:404364	8/26 (31%)
		C2H2 Zn finger	664..684	CDD:275368	8/21 (38%)
		C2H2 Zn finger	717..737	CDD:275368	4/19 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24399
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100