DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10321 and Zbtb6

DIOPT Version :9

Sequence 1:	NP_001261124.1	Gene:	CG10321 / 37464	FlyBaseID:	FBgn0034643	Length:	855	Species:	Drosophila melanogaster
Sequence 2:	NP_666365.1	Gene:	Zbtb6 / 241322	MGIID:	2442998	Length:	423	Species:	Mus musculus

Alignment Length:	360	Identity:	82/360 - (22%)
Similarity:	124/360 - (34%)	Gaps:	110/360 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   384 VMINEDLTQSESQDHEYFDDLDQQQAMDEIEDEEEQMKPEEDQDTFIIEEIQLEDDEMLDDPDGE 448
            |.|.|..|::.|:..|....:...|..|..:..:..:|.||                       |
Mouse   113 VHIVEKCTEALSKYLEIDLSMKNNQHTDLCQSSDTDVKNEE-----------------------E 154

  Fly   449 EIDQDCEYIGEEQDPHLSGDVDDDLEYSIMEPPDGETSVDIDQA--FMDSEQSHHQQ-------- 503
            ..|:|||.|      .:|.|...:|::.:.|    |.|..:..|  .:.||:...|.
Mouse   155 NSDKDCEII------EISEDSPVNLDFHVKE----EESNALQSAAETLTSERMRMQSPELSAVDG 209

  Fly   504 ----------HQEEMQSISLENAVVEFSQATTTTEALVGPTMTVSSASPTPKRAKRSNHQIPAGV 558
                      |.|.:.:..:||.  :|||..|:::|.:....|..|.         .|..:...|
Mouse   210 GFKENEICILHVESISTDDVENG--QFSQPCTSSKAGIYFPETQHSL---------INSTVENRV 263

  Fly   559 TLEPCDHQPPAAGSTTSSKLAAANSRQLVQTASVIAAAGADDNYEIDANLVTEFIRQHTSP---- 619
            |..|         ..|:..|.:.||.....|.:.|  ...|:|:.:          :|..|
Mouse   264 TEVP---------GNTNQGLFSENSDGSHGTVNEI--QNLDENFSL----------RHQCPRCPR 307

  Fly   620 --LGSGRYICHL----------CSTEFRQFKGLQNHMHSHTNWIRANCKKQP-QCQICLKSFKGP 671
              |....|:.||          |...|.|.|.|..|:..|.. ||      | ||.:|||:|...
Mouse   308 GFLHVENYLRHLKMHKLFLCLQCGKTFTQKKNLNRHIRGHMG-IR------PFQCTVCLKTFTAK 365

  Fly   672 GMLRMHMKTHDAESSTPMCTICNRTFKSKAILYRH 706
            ..|:.|:..|..:... .|..|:..||.|:.|.:|
Mouse   366 STLQDHLNIHSGDRPY-KCHCCDMDFKHKSALKKH 399

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10321	NP_001261124.1	zf-AD	12..80	CDD:214871
		ASF1_hist_chap	<405..516	CDD:304562	24/130 (18%)
		C2H2 Zn finger	627..647	CDD:275368	8/29 (28%)
		C2H2 Zn finger	661..681	CDD:275368	7/19 (37%)
		C2H2 Zn finger	690..710	CDD:275368	7/17 (41%)
		C2H2 Zn finger	717..740	CDD:275368
		C2H2 Zn finger	750..767	CDD:275368
Zbtb6	NP_666365.1	BTB	23..123	CDD:279045	4/9 (44%)
		BTB	34..127	CDD:197585	5/13 (38%)
		C2H2 Zn finger	302..322	CDD:275368	5/19 (26%)
		zf-C2H2	325..347	CDD:278523	6/21 (29%)
		C2H2 Zn finger	327..347	CDD:275368	6/19 (32%)
		zf-H2C2_2	339..363	CDD:290200	11/30 (37%)
		C2H2 Zn finger	355..375	CDD:275368	7/19 (37%)
		C2H2 Zn finger	383..400	CDD:275368	7/17 (41%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24399
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100