DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10321 and Zfp958

DIOPT Version :9

Sequence 1:	NP_001261124.1	Gene:	CG10321 / 37464	FlyBaseID:	FBgn0034643	Length:	855	Species:	Drosophila melanogaster
Sequence 2:	NP_001355333.1	Gene:	Zfp958 / 233987	MGIID:	2385298	Length:	489	Species:	Mus musculus

Alignment Length:	163	Identity:	50/163 - (30%)
Similarity:	76/163 - (46%)	Gaps:	18/163 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   614 RQHTSPLGSGRYICHLCSTEFRQFKGLQNHMHSHTNWIRANCKKQPQCQICLKSFKGPGMLRMHM 678
            |.||   |...|.|:.|...|.....|:.|..:||.      :|..:|..|.|:||....||:|.
Mouse   285 RTHT---GEKPYECNQCGKAFSDHHTLRIHERAHTG------EKPFECNQCGKTFKLHSQLRIHK 340

  Fly   679 KTHDAESSTPMCTICNRTFKSKAILYRHRQTHQ-QRAYCCGVANCRKNFSSAVNLKWHVERKHPE 742
            :||..|.... |..|.:||...:...:|::.|. ::.|.|.  .|.|.|:....|:.| ||.|
Mouse   341 RTHTGEKPHE-CNQCGKTFACPSSFQKHKRIHTGEKPYECN--QCLKAFAYHSRLRKH-ERTH-- 399

  Fly   743 VVDPLFKCGECGSLYDNVDSLQLHVESTDHSAE 775
            ..:..|:|.:||.::...:|||:|..:  |:.|
Mouse   400 TGEKPFRCNQCGKIFSQSNSLQVHKRT--HTGE 430

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10321	NP_001261124.1	zf-AD	12..80	CDD:214871
		ASF1_hist_chap	<405..516	CDD:304562
		C2H2 Zn finger	627..647	CDD:275368	5/19 (26%)
		C2H2 Zn finger	661..681	CDD:275368	8/19 (42%)
		C2H2 Zn finger	690..710	CDD:275368	5/19 (26%)
		C2H2 Zn finger	717..740	CDD:275368	8/22 (36%)
		C2H2 Zn finger	750..767	CDD:275368	6/16 (38%)
Zfp958	NP_001355333.1	KRAB	26..66	CDD:334504
		C2H2 Zn finger	103..119	CDD:275368
		COG5048	125..484	CDD:227381	50/163 (31%)
		C2H2 Zn finger	127..147	CDD:275368
		C2H2 Zn finger	155..175	CDD:275368
		C2H2 Zn finger	183..203	CDD:275368
		C2H2 Zn finger	211..231	CDD:275368
		C2H2 Zn finger	239..259	CDD:275368
		C2H2 Zn finger	267..287	CDD:275368	1/1 (100%)
		C2H2 Zn finger	295..315	CDD:275368	5/19 (26%)
		C2H2 Zn finger	323..343	CDD:275368	8/19 (42%)
		C2H2 Zn finger	351..371	CDD:275368	5/19 (26%)
		C2H2 Zn finger	379..399	CDD:275368	8/22 (36%)
		C2H2 Zn finger	407..427	CDD:275368	7/21 (33%)
		C2H2 Zn finger	435..455	CDD:275368
		C2H2 Zn finger	463..483	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24399
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100