DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG10321 and ZBTB1

DIOPT Version :9

Sequence 1:NP_001261124.1 Gene:CG10321 / 37464 FlyBaseID:FBgn0034643 Length:855 Species:Drosophila melanogaster
Sequence 2:NP_001116801.1 Gene:ZBTB1 / 22890 HGNCID:20259 Length:713 Species:Homo sapiens


Alignment Length:468 Identity:87/468 - (18%)
Similarity:159/468 - (33%) Gaps:157/468 - (33%)


- Green bases have known domain annotations that are detailed below.


  Fly   340 EVEDEELED--VYEQLDSKADHSFETIVLDDDQQQDFLKDHHEHHQVMINEDLTQSESQDHEYFD 402
            ::..:||:|  :.:..|...:.|.:...|:|:.::.|       ::..:.||::..:|.....  
Human   333 DIPTDELKDFNIIKVTDKDCNESTDNDELEDEPEEPF-------YRYYVEEDVSIKKSGRKTL-- 388

  Fly   403 DLDQQQAMDEIEDEE---EQMKP-------EEDQDTFIIEEIQL---EDD--------------- 439
                :..|....||.   |.|:|       :||.:....|...|   |:|               
Human   389 ----KPRMSVSADERGGLENMRPPNNSSPVQEDAENASCELCGLTITEEDLSSHYLAKHIENICA 449

  Fly   440 -----EMLDDPDGEEIDQDCEYIGEEQDPHLSGDVDDDLEYSIMEPPDGETSV-DIDQAFMDSEQ 498
                 ::|  ..|.::.:..:..||.||..::|..:.:.:..:.|.||.::.: |:....:|..:
Human   450 CGKCGQIL--VKGRQLQEHAQRCGEPQDLTMNGLGNTEEKMDLEENPDEQSEIRDMFVEMLDDFR 512

  Fly   499 SHHQQHQEEMQSISLENAVVEFSQATTTTEALVGPTMTVSSASPTPKRAKRSNHQIPAGVTLEPC 563
            .:|.|    :.||                                 ::.:...|        ..|
Human   513 DNHYQ----INSI---------------------------------QKKQLFKH--------SAC 532

  Fly   564 DHQPPAAGSTTSSKLAAANSRQLVQTASVIA--AAGADDNYEIDANLVTEFIRQHTSPLGSGRYI 626
            ..:.|..|             |..:|.:::.  .:...|.....:.::.|..|.|..     ::.
Human   533 PFRCPNCG-------------QRFETENLVVEHMSSCLDQDMFKSAIMEENERDHRR-----KHF 579

  Fly   627 CHLCSTEFRQFKGLQNHMHSHTNWIRANCKKQPQCQICLKSFKGPGMLRMH-------------- 677
            |:||...|.|...|:.|...||.      :||..||.|.|.|.....||:|              
Human   580 CNLCGKGFYQRCHLREHYTVHTK------EKQFVCQTCGKQFLRERQLRLHNDMHKGMARYVCSI 638

  Fly   678 -----MKTHD--------AESSTPMCTICNRTFKSKAILYRHRQTHQQRAYCCGVA----NCRKN 725
                 .:.||        ..:...:|.:|.:.|.:...|.:|...|   .|.||:.    |.||:
Human   639 CDQGNFRKHDHVRHMISHLSAGETICQVCFQIFPNNEQLEQHMDVH---LYTCGICGAKFNLRKD 700

  Fly   726 FSSAVNLKWHVER 738
            ..|..|.| |::|
Human   701 MRSHYNAK-HLKR 712

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG10321NP_001261124.1 zf-AD 12..80 CDD:214871
ASF1_hist_chap <405..516 CDD:304562 28/144 (19%)
C2H2 Zn finger 627..647 CDD:275368 7/19 (37%)
C2H2 Zn finger 661..681 CDD:275368 8/38 (21%)
C2H2 Zn finger 690..710 CDD:275368 5/19 (26%)
C2H2 Zn finger 717..740 CDD:275368 10/26 (38%)
C2H2 Zn finger 750..767 CDD:275368
ZBTB1NP_001116801.1 BTB_POZ_ZBTB1 3..116 CDD:349501
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 160..179
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 270..320
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 384..416 6/37 (16%)
C2H2 Zn finger 536..574 CDD:275368 7/50 (14%)
C2H2 Zn finger 580..600 CDD:275368 7/19 (37%)
C2H2 Zn finger 608..628 CDD:275368 8/19 (42%)
C2H2 Zn finger 636..656 CDD:275368 2/19 (11%)
C2H2 Zn finger 664..684 CDD:275368 5/19 (26%)
C2H2 Zn finger 688..709 CDD:275371 8/21 (38%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR24399
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
11.100

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