DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10321 and Bcl6b

DIOPT Version :9

Sequence 1:	NP_001261124.1	Gene:	CG10321 / 37464	FlyBaseID:	FBgn0034643	Length:	855	Species:	Drosophila melanogaster
Sequence 2:	NP_031554.1	Gene:	Bcl6b / 12029	MGIID:	1278332	Length:	474	Species:	Mus musculus

Alignment Length:	273	Identity:	66/273 - (24%)
Similarity:	108/273 - (39%)	Gaps:	55/273 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   518 VEFSQATTTTEALVGPTMTVSSASPTPKRAKRSNHQIPAGVTLEPCDHQPPAAGSTT---SSKLA 579
            :..:..|:...:|||.    ||..|.|:.      ::|:|.  |.|.....:...||   .|:|:
Mouse   200 IVLNSQTSQAGSLVGE----SSGQPCPQA------RLPSGD--EACSSSSSSEEGTTPGLQSRLS 252

  Fly   580 AANSRQLVQTASVIAAAGADDNYEI-----DANLVTEFIRQHTSPLGSGRYICHLCSTEFRQFKG 639
            .|.:     ||.....|.|:::|..     :.:|...  :|...|.||..:.|..|........|
Mouse   253 LATT-----TARFKCGALANNSYLFTPRAQETSLPAS--KQANPPPGSEFFSCQNCEAVAGCSSG 310

  Fly   640 LQNHMHSHTNWIRANCKKQP-QCQICLKSFKGPGMLRMHMKTHDAESSTPMCTICNRTFKSKAIL 703
            |:        .:....:.:| :||:|..:|:..|.|..|...|..|... .|:||...|...|.|
Mouse   311 LE--------LLAPGDEDKPYKCQLCRSAFRYKGNLASHRTVHTGEKPY-RCSICGARFNRPANL 366

  Fly   704 YRHRQTHQ-QRAYCCGVANCRKNFSSAVNLKWHV-----ERKHPEVVDPLFKCGECGSLYDNVDS 762
            ..|.:.|. ::.|.|  ..|...|....:|:.||     |:.:|        |..||:.:.::.:
Mouse   367 KTHSRIHSGEKPYKC--ETCGSRFVQVAHLRAHVLIHTGEKPYP--------CPTCGTRFRHLQT 421

  Fly   763 LQLHVESTDHSAE 775
            |:.||..  |:.|
Mouse   422 LKSHVRI--HTGE 432

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10321	NP_001261124.1	zf-AD	12..80	CDD:214871
		ASF1_hist_chap	<405..516	CDD:304562
		C2H2 Zn finger	627..647	CDD:275368	4/19 (21%)
		C2H2 Zn finger	661..681	CDD:275368	7/19 (37%)
		C2H2 Zn finger	690..710	CDD:275368	7/19 (37%)
		C2H2 Zn finger	717..740	CDD:275368	7/27 (26%)
		C2H2 Zn finger	750..767	CDD:275368	4/16 (25%)
Bcl6b	NP_031554.1	BTB	28..132	CDD:279045
		BTB	39..131	CDD:197585
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	144..190
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	210..249		13/50 (26%)
		C2H2 Zn finger	325..345	CDD:275368	7/19 (37%)
		zf-H2C2_2	337..362	CDD:290200	8/25 (32%)
		C2H2 Zn finger	353..373	CDD:275368	7/19 (37%)
		zf-H2C2_2	365..390	CDD:290200	7/26 (27%)
		C2H2 Zn finger	381..401	CDD:275368	6/21 (29%)
		zf-H2C2_2	393..418	CDD:290200	8/32 (25%)
		C2H2 Zn finger	409..429	CDD:275368	6/21 (29%)
		zf-H2C2_2	422..446	CDD:290200	5/13 (38%)
		C2H2 Zn finger	437..455	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24399
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100