DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10321 and OSR2

DIOPT Version :9

Sequence 1:	NP_001261124.1	Gene:	CG10321 / 37464	FlyBaseID:	FBgn0034643	Length:	855	Species:	Drosophila melanogaster
Sequence 2:	NP_001273770.1	Gene:	OSR2 / 116039	HGNCID:	15830	Length:	433	Species:	Homo sapiens

Alignment Length:	151	Identity:	41/151 - (27%)
Similarity:	64/151 - (42%)	Gaps:	17/151 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   625 YICHLCSTEFRQFKGLQNHMHSHTNWIRANCKKQPQCQICLKSFKGPGMLRMHMKTHDAESSTPM 689
            :||..|...|.:...|..|..:||:      ::...|.||.|:|:....||.|...|..|.  |.
Human   293 FICKFCGRHFTKSYNLLIHERTHTD------ERPYTCDICHKAFRRQDHLRDHRYIHSKEK--PF 349

  Fly   690 -CTICNRTFKSKAILYRHRQTHQQRA-YCCGVANCRKNFSSAVNLKWHVERKHPEVVDPLFKCGE 752
             |..|.:.|.....|..|:..|.|.: :.|  ..|.:.|:...|||.|: ..|.::..  :.|.:
Human   350 KCQECGKGFCQSRTLAVHKTLHMQESPHKC--PTCGRTFNQRSNLKTHL-LTHTDIKP--YSCEQ 409

  Fly   753 CGSLYDNVDSLQLHVESTDHS 773
            ||.::.....|:.|  |..|:
Human   410 CGKVFRRNCDLRRH--SLTHT 428

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10321	NP_001261124.1	zf-AD	12..80	CDD:214871
		ASF1_hist_chap	<405..516	CDD:304562
		C2H2 Zn finger	627..647	CDD:275368	5/19 (26%)
		C2H2 Zn finger	661..681	CDD:275368	8/19 (42%)
		C2H2 Zn finger	690..710	CDD:275368	5/19 (26%)
		C2H2 Zn finger	717..740	CDD:275368	7/22 (32%)
		C2H2 Zn finger	750..767	CDD:275368	4/16 (25%)
OSR2	NP_001273770.1	COG5048	<293..428	CDD:227381	40/149 (27%)
		C2H2 Zn finger	295..315	CDD:275368	5/19 (26%)
		zf-H2C2_2	307..332	CDD:290200	9/30 (30%)
		C2H2 Zn finger	323..343	CDD:275368	8/19 (42%)
		zf-H2C2_2	335..358	CDD:290200	8/24 (33%)
		C2H2 Zn finger	351..371	CDD:275368	5/19 (26%)
		zf-C2H2	377..399	CDD:278523	7/24 (29%)
		C2H2 Zn finger	379..399	CDD:275368	7/22 (32%)
		zf-H2C2_2	391..416	CDD:290200	8/27 (30%)
		C2H2 Zn finger	407..427	CDD:275368	6/21 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	0	0.000