DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10321 and bif1.1

DIOPT Version :9

Sequence 1:	NP_001261124.1	Gene:	CG10321 / 37464	FlyBaseID:	FBgn0034643	Length:	855	Species:	Drosophila melanogaster
Sequence 2:	XP_001922816.3	Gene:	bif1.1 / 103908654	ZFINID:	ZDB-GENE-081031-77	Length:	346	Species:	Danio rerio

Alignment Length:	257	Identity:	67/257 - (26%)
Similarity:	94/257 - (36%)	Gaps:	53/257 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   543 TPKRA--------KRSNHQIPAGVTLEPCD-------HQPPAAGSTTSSKLAAAN-----SRQLV 587
            |.|||        ||:..:.|...|.|..|       .||.|..:....|.|.:.     ||:..
Zfish    15 TKKRAGAVKANKDKRNRFKKPLDATKENADKVTEKTQRQPKAQKTDVKKKFACSECEKSYSRKPD 79

  Fly   588 QTASV----------IAAAGAD--DNYEIDANLVTEFIRQHTSPLGSGRYICHLCSTEFRQFKGL 640
            .|..:          ....|.|  |..::|.::     |.||   |...:.|.:|...:.....|
Zfish    80 LTRHMRFHTGENLLTCTQCGKDFTDKVKLDIHM-----RLHT---GERPHACKMCGQTYIHLGDL 136

  Fly   641 QNHMHSHTNWIRANCKKQPQCQICLKSFKGPGMLRMHMKTHDAESSTPMCTICNRTFKSKAILYR 705
            ..||..||.      :|...|..|...|.....|:.||..|..|.....||.|.:::.||..|..
Zfish   137 TRHMRVHTG------EKPYSCAQCGHKFIDTNALKYHMTIHTGEKRMFACTQCEKSYTSKTQLLN 195

  Fly   706 HRQTHQ-QRAYCCGVANCRKNFSSAVNLKWHVERKHPEVVDPLFKCGECGSLYDNVDSLQLH 766
            |:..|. .:::.|.  .|.|.|:....|:.|  ||....|.|.| | .||..|.::..|:.|
Zfish   196 HQLYHTGVKSFSCD--QCDKTFTLLTYLQRH--RKVHAAVKPHF-C-FCGRGYTSMQKLKEH 251

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10321	NP_001261124.1	zf-AD	12..80	CDD:214871
		ASF1_hist_chap	<405..516	CDD:304562
		C2H2 Zn finger	627..647	CDD:275368	5/19 (26%)
		C2H2 Zn finger	661..681	CDD:275368	6/19 (32%)
		C2H2 Zn finger	690..710	CDD:275368	7/19 (37%)
		C2H2 Zn finger	717..740	CDD:275368	7/22 (32%)
		C2H2 Zn finger	750..767	CDD:275368	6/17 (35%)
bif1.1	XP_001922816.3	COG5048	<63..251	CDD:227381	53/207 (26%)
		C2H2 Zn finger	67..87	CDD:275368	3/19 (16%)
		C2H2 Zn finger	95..115	CDD:275368	5/24 (21%)
		C2H2 Zn finger	123..143	CDD:275368	5/19 (26%)
		zf-H2C2_2	135..158	CDD:290200	8/28 (29%)
		C2H2 Zn finger	151..171	CDD:275368	6/19 (32%)
		C2H2 Zn finger	180..200	CDD:275368	7/19 (37%)
		C2H2 Zn finger	208..227	CDD:275368	7/22 (32%)
		C2H2 Zn finger	238..255	CDD:275368	5/14 (36%)
		C2H2 Zn finger	263..283	CDD:275368
		C2H2 Zn finger	291..311	CDD:275368
		C2H2 Zn finger	319..337	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24399
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.100