DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10321 and zbtb14

DIOPT Version :9

Sequence 1:	NP_001261124.1	Gene:	CG10321 / 37464	FlyBaseID:	FBgn0034643	Length:	855	Species:	Drosophila melanogaster
Sequence 2:	XP_002938096.1	Gene:	zbtb14 / 100487514	XenbaseID:	XB-GENE-968315	Length:	452	Species:	Xenopus tropicalis

Alignment Length:	409	Identity:	92/409 - (22%)
Similarity:	159/409 - (38%)	Gaps:	71/409 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   349 VYEQLDSKADHSFETIVLDDDQQQDFLKDHHEHHQVMINEDLTQSESQDH----EYFDDL-DQQQ 408
            ::::|:..:....|...|..|..::.|...:.....:..||:....|...    .:.|.| .|::
Frog    64 LFKKLEVDSSSVIEIDFLRSDIFEEVLNYMYTAKIAVKKEDVNLMMSSGQILGIRFLDKLCSQKR 128

  Fly   409 AMDEIEDEEEQMKPEEDQDTFIIEEIQLEDDEMLDDPDGE---EIDQDCEYIGEEQDPHLSGDVD 470
            .:..|::.....|.:...:|.:          .:..|.||   ..|.:.|.|| :||...|.|..
Frog   129 DVSSIDENPASPKNKYSYETSL----------KITRPVGEANDNQDDEVEEIG-DQDDSPSDDTV 182

  Fly   471 DDLEYSIMEPPDGETSVDIDQAFMDSEQSHHQQHQEEMQSISLENAVVEFSQATTTTEALVGPTM 535
            :....|..|.....:::.:.:|.:....|      ||::.::.....|| :..||..:.|...|.
Frog   183 EGTPQSHEEEKSPTSTLRVQEAILKELGS------EEVRKVNCYGQEVE-AMETTEPKDLGSQTQ 240

  Fly   536 TVSSASPTPKRAKRSNHQIPAGVTLEPCDHQPPAAGSTTSSK----LAAANSRQLVQTASVIAAA 596
            |::           .|..|.     |..|.|.||..:.||..    |...:..|       .|..
Frog   241 TLT-----------FNDSIS-----EVKDEQAPAWTTATSDMKFEYLLYGHREQ-------FACQ 282

  Fly   597 GADDNYEIDANLVTEFIRQHTSPLGSGR-YICHLCSTEFRQFKGLQNHMHSHTNWIRANCKKQPQ 660
            .....:..:|.|     |:|.....:.| ::|.:|:..|.....|:.|:..||.:      |...
Frog   283 ACGKTFTDEARL-----RKHEKLHTADRPFVCEMCAKAFTTQAHLKEHLKIHTGY------KPYS 336

  Fly   661 CQICLKSFKGPGMLRMHMKTHDAESSTPM-CTICNRTFKSKAILYRHRQTHQ-QRAYCCGVANCR 723
            |::|.|||.....|:.|.:.|..|  .|. |.:|::.||.|:.|..|.:.|: ::.:.|  |:|.
Frog   337 CEVCAKSFIRAPDLKKHERVHSNE--RPFACHLCDKAFKHKSHLKDHERRHRGEKPFIC--ASCT 397

  Fly   724 KNFSSAVNLKWHVERKHPE 742
            |.|:.|.:||.|....|.|
Frog   398 KAFAKASDLKRHENNMHSE 416

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10321	NP_001261124.1	zf-AD	12..80	CDD:214871
		ASF1_hist_chap	<405..516	CDD:304562	21/113 (19%)
		C2H2 Zn finger	627..647	CDD:275368	5/19 (26%)
		C2H2 Zn finger	661..681	CDD:275368	7/19 (37%)
		C2H2 Zn finger	690..710	CDD:275368	7/19 (37%)
		C2H2 Zn finger	717..740	CDD:275368	9/22 (41%)
		C2H2 Zn finger	750..767	CDD:275368
zbtb14	XP_002938096.1	BTB_POZ_ZBTB14	18..131	CDD:349513	11/66 (17%)
		C2H2 Zn finger	281..301	CDD:275368	4/24 (17%)
		SFP1	<305..385	CDD:227516	26/87 (30%)
		C2H2 Zn finger	309..329	CDD:275368	5/19 (26%)
		C2H2 Zn finger	337..357	CDD:275368	7/19 (37%)
		SUF4-like	361..>421	CDD:411020	20/58 (34%)
		C2H2 Zn finger	365..385	CDD:411020	7/19 (37%)
		C2H2 Zn finger	365..385	CDD:275368	7/19 (37%)
		C2H2 Zn finger	393..414	CDD:411020	9/22 (41%)
		C2H2 Zn finger	393..409	CDD:275368	8/17 (47%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24399
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100