Protein Alignment PTP-ER and PTPN5

DIOPT Version :9

• Sequence 1: NP_726092.1
• Gene: PTP-ER / 37461
• FlyBaseID: FBgn0016641
• Length: 1377
• Species: Drosophila melanogaster
• Sequence 2: XP_016873923.1
• Gene: PTPN5 / 84867
• HGNCID: 9657
• Length: 719
• Species: Homo sapiens
• Alignment Length: 429
• Identity: 111/429 - (25%)
• Similarity: 151/429 - (35%)
• Gaps: 168/429 - (39%)

  Fly   843 GSNARDVETPTDMVPPS----------SEDSELLASYQTVVSRMAQPIPELKENEQKRIFRDLHK 897
            |||   |....||..|.          |...|....|....||:.| ..||.|.......  |..
Human   244 GSN---VSLTLDMCTPGCNEEGFGYLMSPREESAREYLLSASRVLQ-AEELHEKALDPFL--LQA 302

  Fly   898 EFWDLPLNHQEKPMVF---GSQTKNRYKTILPNENSRVLLESESSE--LTSLLGEIKRTSSVTAS 957
            ||:::|:|..: |..:   |...||||||||||.:|||.|.|...:  |:|
Human   303 EFFEIPMNFVD-PKEYDIPGLVRKNRYKTILPNPHSRVCLTSPDPDDPLSS-------------- 352

  Fly   958 EDLPYINANYIKGPDYVSKCYVATQGPLPNTIFEFWLMIYQNTQRYIRRCVDGGSSSSPHVDREQ 1022
                |||||||:|.....|.|:|||||:.:|:.:||.|::
Human   353 ----YINANYIRGYGGEEKVYIATQGPIVSTVADFWRMVW------------------------- 388

  Fly  1023 ILQQYFQKIVMLTNFTEANRQKCAVYFP--------IELN----------EIFAVAAKCEVFQLS 1069
              |::...|||:||..|.| :||..|:|        :|:.          .:..::.||
Human   389 --QEHTPIIVMITNIEEMN-EKCTEYWPEEQVAYDGVEITVQKVIHTEDYRLRLISLKC------ 444

  Fly  1070 AAARDYFDR------YLTPTFV--------PDTVVASSDAIDYEISGRH---------------- 1104
               ||:.||      :|.|...        .|.|.|.|.      .|||
Human   445 ---RDWEDRLLHCHQHLLPAAAAGGCGGHPEDHVPAPSG------QGRHDPDMRAVPVCAPRHEP 500

  Fly  1105 ---IGVESV----KVTLEGDLLEALPAQ--GSFFLIKNVGIVRRNGYSVRKLVLLYCIRVPQSAS 1160
               ..|..|    .:.|:|.|..|.|..  ....|.:.:|::..:..||..|    |   |.||
Human   501 LRKAAVPPVPRMTALLLQGSLGTAQPESRPSPRALPRVLGLLPASSPSVSSL----C---PLSA- 557

  Fly  1161 YHLQKIYCYHYWYPDWPDHHSPRDINTLLDTCLHVLNLG 1199
                           |||.:.|     .|...|::|..|
Human   558 ---------------WPDPYPP-----ALLFLLYILGSG 576

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PTP-ER	NP_726092.1	Y_phosphatase	916..1364	CDD:278528	88/343 (26%)
		PTPc	917..1364	CDD:238006	88/342 (26%)
PTPN5	XP_016873923.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0789
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	220	1.000	Inparanoid score	I3565
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	3	2.910