Protein Alignment PTP-ER and PTPRG

DIOPT Version :9

• Sequence 1: NP_726092.1
• Gene: PTP-ER / 37461
• FlyBaseID: FBgn0016641
• Length: 1377
• Species: Drosophila melanogaster
• Sequence 2: XP_016862450.1
• Gene: PTPRG / 5793
• HGNCID: 9671
• Length: 1485
• Species: Homo sapiens
• Alignment Length: 547
• Identity: 123/547 - (22%)
• Similarity: 186/547 - (34%)
• Gaps: 236/547 - (43%)

  Fly   829 YQTNRNIIEQPPVLGSNARDVETPTDMVP--PSSEDSELLASYQTVVSRMAQPIPELKENEQ--- 888
            :||....:|.    .|:.|.|  |.:.:|  |..:|.|.:.     |.:..:.|.||..|.|
Human   835 FQTAHFYVED----SSSPRVV--PNESIPIIPIPDDMEAIP-----VKQFVKHIGELYSNNQHGF 888

  Fly   889 KRIFRDLHKEFWDLPL-----NHQEKPMVFGSQTKNRYKTILPNENSRVLLESESSELTSLLGEI 948
            ...|.::.:...|:.:     ||.|      ::.||||..||..::|||       :|..|.|:.
Human   889 SEDFEEVQRCTADMNITAEHSNHPE------NKHKNRYINILAYDHSRV-------KLRPLPGKD 940

  Fly   949 KRTSSVTASEDLPYINANYIKGPDYVSKCYVATQGPLPNTIFEFWLMIY-QNTQRYIRRCVDGGS 1012
            .:.|.        ||||||:.|.: .:|.|:||||||.:|..:||.||: |||
Human   941 SKHSD--------YINANYVDGYN-KAKAYIATQGPLKSTFEDFWRMIWEQNT------------ 984

  Fly  1013 SSSPHVDREQILQQYFQKIVMLTNFTEANRQKCAVYFPIELNEIFAVAAKCEVFQLSAAARDYFD 1077
                            ..|||:||..|..|:||..|:|.|.:|.:.
Human   985 ----------------GIIVMITNLVEKGRRKCDQYWPTENSEEYG------------------- 1014

  Fly  1078 RYLTPTFVPDTVVASSDAIDYEISGRHIGVESVKVTLEGDLLEALPAQGSFFLIKNVGIVRRNGY 1142
                                           ::.|||:...:.|...            |||  :
Human  1015 -------------------------------NIIVTLKSTKIHACYT------------VRR--F 1034

  Fly  1143 SVRKLVLLYCIRVPQSASYHLQKIYCYHYWYPDWPDHHSPRDINTLLDTCLHVLNLGKCESEFDI 1207
            |:|...:....:.......:.:.:..||  |..|||...|       :..|.||...:..|
Human  1035 SIRNTKVKKGQKGNPKGRQNERVVIQYH--YTQWPDMGVP-------EYALPVLTFVRRSS---- 1086

  Fly  1208 YDDTRSERNAHLAAQRLEIYQQDIFNAVQPLPVIHCSAGIGRTGCFTAILNAVRQLRQSLAYSLT 1272
                        ||:..|         ..|: ::|||||:||||.:..|.:.::|::
Human  1087 ------------AARMPE---------TGPV-LVHCSAGVGRTGTYIVIDSMLQQIK-------- 1121

  Fly  1273 GMLTKSLTSSSTEEYHNPTDSDSSFTCNTIRHISHILDHRDAEAVKTPPSFDRLPKMPDIFVDVL 1337
                    ..||                                                 |:||
Human  1122 --------DKST-------------------------------------------------VNVL 1129

  Fly  1338 GIVCNLRLQRGGMVQNSEQYELIHRAI 1364
            |.:.::|.||..:||..|||..||.|:
Human  1130 GFLKHIRTQRNYLVQTEEQYIFIHDAL 1156

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PTP-ER	NP_726092.1	Y_phosphatase	916..1364	CDD:278528	100/448 (22%)
		PTPc	917..1364	CDD:238006	100/447 (22%)
PTPRG	XP_016862450.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0789
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900