Protein Alignment PTP-ER and ptprga

DIOPT Version :10

• Sequence 1: NP_726092.1
• Gene: PTP-ER / 37461
• FlyBaseID: FBgn0016641
• Length: 1377
• Species: Drosophila melanogaster
• Sequence 2: NP_001316793.1
• Gene: ptprga / 561197
• ZFINID: ZDB-GENE-101101-4
• Length: 1414
• Species: Danio rerio
• Alignment Length: 1147
• Identity: 224/1147 - (19%)
• Similarity: 356/1147 - (31%)
• Gaps: 424/1147 - (36%)

  Fly   357 VIHHHLHLQQPASAIHSTSLSRLDSHLSLANQRRTPRRKSPGINTTDWLMYHR------KQNP-- 413
            |:||..........:.....|.:.|:........||    |.....:|:::.|      ||..
Zfish   224 VVHHEKETFLEPFVLRDLLPSSIGSYYRYIGSLTTP----PCSKVVEWIVFSRPVLLSYKQLEAF 284

  Fly   414 YQV----QPTHCSSTTQ--------SSLDSDASLTPSLGDFELKSACSVDGGSKFGIGASLAPRS 466
            |.:    |..|..|...        .|||:......::.|..|.. .:...|:.:|..||.|..|
Zfish   285 YSIFTTEQQDHVKSVEYLRNNFRPLQSLDNREVFKSAVKDAWLPD-LTYPPGNPYGTEASKACSS 348

  Fly   467 AHKHNQLLHSSSTNLK---TLPEC---------LTLVEFSSSGGGPKESPFKQKSMDLPMPTLQA 519
            |..:..:.|.:.|.|.   :.||.         |....::.:....:|:.||.....|.    ..
Zfish   349 APINMNVQHMNKTALVVRWSRPEITYDPPIISYLISYSWTRNDESYEETYFKGSDQKLE----AV 409

  Fly   520 KTTVSTSSMNLLQRRGSNHSLTLNLHSSCGNLMNSGLSHSNYSLGSILNSKSSCNLDAGT----- 579
            .|.||...:.|.:           :.:.|.|...|..|.      |:|...::..:..||
Zfish   410 ITPVSPDVLYLFR-----------VQAVCLNDKRSDFSQ------SMLFRANTTRIFEGTRIVKT 457

  Fly   580 -------ASQIRADQLPQSHLLGSSQGSRQGL----------FRRRGSNHSITLKTGHTTTSCGD 627
                   ||.  ||..|.|.  |||..:..||          .....|....|:.:..|:|....
Zfish   458 GMPTVSPASS--ADMAPISS--GSSTWTSSGLPFSFVSMATGIGPSSSGSQATVASVVTSTLLAG 518

  Fly   628 LN--------------------------SMQQLQQQQAMLSAEKYNRL-------NMRTNSTGSG 659
            |.                          |..|...:..:.:||:.:..       |.|::..|..
Zfish   519 LGFSGGVISSFPSSVWPTRPPPSSPAPASTHQSPAKPVVTTAEQASDADTTTATDNDRSDDGGEK 583

  Fly   660 SGSGSNVPTPKRGLLERRGSNQSLTLNMGSILGGAAGTEIQMTDIVQ----------PKVTVCSC 714
            .|.|.:....|.|..|.....:.          |....:.:..|.|:          |...|...
Zfish   584 GGKGEDEDGEKNGEEEEDEDEEK----------GGESKDSRAPDDVEKQTNSSVSKDPPTAVPDS 638

  Fly   715 AAANQAPHQRKFFSTENLNSSKANSQKFFGQVCFGSASDLQPNPQQDSVREDQAIGATCTCAGTV 779
            .|..:...:|...||.....|:.|:|        |...:   |.|..:.||.:.       ...|
Zfish   639 TAKEKGGRRRTENSTAPSRVSEENTQ--------GLGEE---NTQVMASREPEV-------EENV 685

  Fly   780 RNIMTRPLSPQTTSEE----------FKIY-----LASIQ--------------MLQSASNPLNQ 815
            ..::..|.:.:.:|::          |.|:     ::|:.              ::.||...|..
Zfish   686 TAVIETPENTEQSSKDNRGDRNHLPPFSIHTERTVVSSMYPGPAAGRMEWIIPLVVVSALTFLCL 750

  Fly   816 FDLIRLNYVFDHSYQTNRNIIEQPPVLGSNARDVETPTDMVP--PSSEDSELLASYQTVVSRMAQ 878
            ..|:.:...:...:||....:|.     ||:..| .|.:.:|  |..:|.|.:.     |....:
Zfish   751 ILLLAVLVYWRRCFQTAHFYVED-----SNSPRV-VPNESIPVIPIPDDMEAIP-----VKHFIK 804

  Fly   879 PIPELKENEQKRI---FRDLHKEFWDLPL--NHQEKPMVFGSQTKNRYKTILPNENSRVLLESES 938
            .:.||..|.|...   |.::.:...|:.:  .|...|   .::.||||..|:..::|||
Zfish   805 HVSELYSNNQHGFSDDFEEVQRCTADMKITAEHSNHP---DNKHKNRYINIIAYDHSRV------ 860

  Fly   939 SELTSLLGEIKRTSSVTASEDLPYINANYIKGPDYVSKCYVATQGPLPNTIFEFWLMIY-QNTQR 1002
             :|..|.|:..:.|.        ||||||:.|.: ..|.|:|.||||.:|..:||.|:: |||
Zfish   861 -KLRPLAGKDSKHSD--------YINANYVDGYN-KPKAYIAAQGPLKSTFEDFWRMVWEQNT-- 913

  Fly  1003 YIRRCVDGGSSSSPHVDREQILQQYFQKIVMLTNFTEANRQKCAVYFPIELNEIFAVAAKCEVFQ 1067
                                      ..|||:||..|..|:||..|:|.|.:|.:.
Zfish   914 --------------------------GIIVMITNLVEKGRRKCDQYWPSENSEEYG--------- 943

  Fly  1068 LSAAARDYFDRYLTPTFVPDTVVASSDAIDYEISGRHIGVESVKVTLEGDLLEALPAQGSFFLIK 1132
                                                     ::.|||:...:.|.... ..|.|:
Zfish   944 -----------------------------------------NIVVTLKRTKVMACYTL-RIFTIR 966

  Fly  1133 NVGIVR-----RNGYSVRKLVLLYCIRVPQSASYHLQKIYCYHYWYPDWPDHHSPRDINTLLDTC 1192
            |..:.:     ..|....:.||          .||          |..|||...|       :..
Zfish   967 NTKVKKGQKGNTKGRQSERTVL----------QYH----------YTQWPDMGVP-------EYT 1004

  Fly  1193 LHVLNLGKCESEFDIYDDTRSERNAHLAAQRLEIYQQDIFNAVQPLPVIHCSAGIGRTGCFTAIL 1257
            |.||...:..|                |||..:         :.|: ::|||||:||||.:..|.
Zfish  1005 LPVLTFVRKSS----------------AAQTPD---------MGPM-LVHCSAGVGRTGTYIVID 1043

  Fly  1258 NAVRQLRQSLAYSLTGMLTKSLTSSSTEEYHNPTDSDSSFTCNTIRHISHILDHRDAEAVKTPPS 1322
            :.::||:...|
Zfish  1044 SMLQQLKDKGA------------------------------------------------------ 1054

  Fly  1323 FDRLPKMPDIFVDVLGIVCNLRLQRGGMVQNSEQYELIHRAI 1364
                       |:|||.:.::|.||..:||..|||..||.|:
Zfish  1055 -----------VNVLGFLKHIRTQRNYLVQTEEQYIFIHDAL 1085

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PTP-ER	NP_726092.1	PTP_DSP_cys	919..1362	CDD:475123	96/448 (21%)
ptprga	NP_001316793.1	alpha_CARP_receptor_like	71..319	CDD:239396	19/98 (19%)
		FN3	348..426	CDD:214495	16/92 (17%)
		R-PTPc-G-1	817..1090	CDD:350505	103/485 (21%)
		R-PTP-G-2	1174..1378	CDD:350508