Protein Alignment PTP-ER and ptpn5

DIOPT Version :9

• Sequence 1: NP_726092.1
• Gene: PTP-ER / 37461
• FlyBaseID: FBgn0016641
• Length: 1377
• Species: Drosophila melanogaster
• Sequence 2: XP_009301648.1
• Gene: ptpn5 / 559524
• ZFINID: ZDB-GENE-101028-3
• Length: 529
• Species: Danio rerio
• Alignment Length: 663
• Identity: 153/663 - (23%)
• Similarity: 211/663 - (31%)
• Gaps: 298/663 - (44%)

  Fly   742 FFGQVCFGSAS-----DLQPNPQQDSVREDQAIGATCTCAGTVRNIMTRPLSPQTTSEEFKIYLA 801
            |.|.|..|:.:     .|.|. .|....||:            |..|:|  .|..|..|:
Zfish   118 FLGVVILGTGTLFCIKTLVPG-NQSCFPEDR------------RQSMSR--QPSFTYSEW----- 162

  Fly   802 SIQMLQSASNPLNQFDLIRLNYVFDHSYQTNRNIIEQPPVL------------GSNARDVETPTD 854
                ..:......:.|.:....|||......   .|..||.            |||   |....|
Zfish   163 ----TDAKQEDFYELDAVPETPVFDCFMDMK---TEADPVTLTVKPVGLQERRGSN---VSLTLD 217

  Fly   855 MVPPSSEDSELLASYQTVVSRMAQPIPELKEN-------EQ--KRIFRD--LHKEFWDLPLNHQE 908
            |..|.:.:     .|..::|...|...|..:|       ||  .|...|  |..||::.|:|..:
Zfish   218 MCTPGTTE-----PYGALLSPREQSTQEYLQNASNLLTPEQLHTRALDDGVLQAEFYETPMNFVD 277

  Fly   909 KPMVF---GSQTKNRYKTILPNENSRVLLESESSELTSLLGEIKRTSSVTASEDLPYINANYIKG 970
             |..:   |...||||||||||.:|||.|:::..      |:...|          ||||||:||
Zfish   278 -PKEYSIPGVVRKNRYKTILPNTHSRVCLKAKEE------GDFLST----------YINANYLKG 325

  Fly   971 PDYVSKCYVATQGPLPNTIFEFWLMIYQNTQRYIRRCVDGGSSSSPHVDREQILQQYFQKIVMLT 1035
            .....|.|:|||||..||:.:||.|::|      .||                     ..|||:|
Zfish   326 YGGKEKAYIATQGPTVNTVGDFWRMVWQ------ERC---------------------PIIVMIT 363

  Fly  1036 NFTEANRQKCAVYFPIELNEIFAVAAKCEVFQLSAAARDYFDRYLTPTFVPDTVVASSDAIDYEI 1100
            |..|.| :||..|:|.:       :..||..::                   ||.....|.||.:
Zfish   364 NIEEKN-EKCTEYWPED-------SVTCEGIEI-------------------TVKQVIQADDYSL 401

  Fly  1101 SGRHIGVESVKVTLEGDLLEALPAQGSFFLIKNVGIVRRNGYSVRKLVLLYCIRVPQSASYHLQK 1165
                                      ..|.:|:.|..|    |:|:
Zfish   402 --------------------------RIFTVKSEGEER----SLRQ------------------- 417

  Fly  1166 IYCYHYWYPDWPDHHSPRDINTLLDTCLHVLNLGKCESEFDIYDDTRSERNAHLAAQRLEIYQQD 1230
                 |||..|||..:|.....||:..                                    |:
Zfish   418 -----YWYTSWPDQKTPDKAPPLLELV------------------------------------QE 441

  Fly  1231 IFNAVQPLP------VIHCSAGIGRTGCFTAILNAVRQLRQSLAYSLTGMLTKSLTSSSTEEYHN 1289
            :..|.:..|      ::||||||||||||.|                |.:|.:.|::...
Zfish   442 VEEARKQAPPNSGPVIVHCSAGIGRTGCFIA----------------TSILCQQLSNEGV----- 485

  Fly  1290 PTDSDSSFTCNTIRHISHILDHRDAEAVKTPPSFDRLPKMPDIFVDVLGIVCNLRLQRGGMVQNS 1354
                                                        ||:|.....|||.||||:|.:
Zfish   486 --------------------------------------------VDILKTTSQLRLDRGGMIQTA 506

  Fly  1355 EQYELIHRAICLY 1367
            |||:.:|..:.||
Zfish   507 EQYQFVHHVLSLY 519

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PTP-ER	NP_726092.1	Y_phosphatase	916..1364	CDD:278528	106/453 (23%)
		PTPc	917..1364	CDD:238006	106/452 (23%)
ptpn5	XP_009301648.1	PTPc	264..516	CDD:214550	113/477 (24%)
		PTPc	289..516	CDD:238006	106/451 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0789
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	216	1.000	Inparanoid score	I3586
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR19134
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	4	4.010