Protein Alignment PTP-ER and ptprz1b

DIOPT Version :10

• Sequence 1: NP_726092.1
• Gene: PTP-ER / 37461
• FlyBaseID: FBgn0016641
• Length: 1377
• Species: Drosophila melanogaster
• Sequence 2: XP_073803012.1
• Gene: ptprz1b / 553019
• ZFINID: ZDB-GENE-050506-100
• Length: 1457
• Species: Danio rerio
• Alignment Length: 1008
• Identity: 202/1008 - (20%)
• Similarity: 344/1008 - (34%)
• Gaps: 368/1008 - (36%)

  Fly   431 SDASLTPSLGDFELKSACSVDGGSKFGIGASLAPRSAHKHNQLLHSSSTNLKTLPECLTLVEFSS 495
            |..|..|..|.|.::     |.||...|     ..|..:...|...|.|...|:...:|
Zfish   437 SAPSSKPPPGRFLIR-----DSGSSISI-----TTSTDQPGFLFPVSRTTPITVRRKIT------ 485

  Fly   496 SGGGPKESPFKQKSMDLPMPTLQAKTTVSTSSMNLLQRRGSNHSLTLNLHSSCGNLMNSGLSHSN 560
                 :||...|       |.:|.|:..:.:      :|.:|..|.    ...|:...|....::
Zfish   486 -----EESSLSQ-------PPVQNKSRKNET------KRPANRLLP----DDSGHFPQSNTVVTD 528

  Fly   561 YSLGSILNSKSSCNLDAGTASQIRADQLPQSHLLGSSQGSRQGLFRRRGSNHSITLKTGHTTTSC 625
            .....:||| |:.|:.....:.:..||..:.   .|:...:|      .:|.|   .|.:.||..
Zfish   529 VYYEDVLNS-STTNITPTINNNLLIDQNTEK---ASTSPPKQ------PANES---STANATTGS 580

  Fly   626 GDLNSMQQLQQ------QQAMLSAEKYN--RLNMRTNSTGSGSGSGSNVPTPKRGLLERRGSNQS 682
            ....||:.:.|      ....::|..:|  |:.|.:::| |...|.:..||.   :||...::..
Zfish   581 SLSASMKIISQTTQPLFNDVFVTATSFNNERVLMVSDAT-SLYESSTRSPTI---ILEEGSAHFP 641

  Fly   683 LTLNMGSILGGAAGTEIQMTD----IVQPKVTVCSCAAANQAPHQRK-----------FFSTENL 732
            .:...|...|..:...::..|    :.|.::     |..|..|.:.:           ||.:|..
Zfish   642 PSDGQGEFSGSGSAIFLEELDREWELEQTRM-----APKNADPRKTQEENHEGLPSTFFFESERE 701

  Fly   733 NSS--KANSQKFFGQVCFGSASD--------------------LQP--NPQQDSVRE------DQ 767
            .||  |..:|.|...|.:.:.||                    :.|  |.|:::..|      :.
Zfish   702 ASSTYKPQNQDFLSWVTWSAESDSGSGQGGSMISQTEDIPIQLIIPKLNIQEENHAEASNSSPES 766

  Fly   768 AIGATCTCAGTVRNIMTRPLSPQTTSEEFKIYLASIQMLQSASNPLNQFDLIRLNYVFDHSYQTN 832
            .:|..   .||            .|.:...:.||.:..|    ..|....|:.:...:...:||.
Zfish   767 RVGMV---GGT------------ETEKRAVVPLAIVSTL----TVLCLVVLVGILIYWRRCFQTA 812

  Fly   833 RNIIEQPPVLGSNARDVETPTDMVPPSSEDSELLASYQTVVSRMAQPIPELKENEQKRIFRDLHK 897
            ...:|..    ::||.:..|:..:...:||:|.| ..:..|..:|......|.:::..|.::.::
Zfish   813 HFYVEDT----NSARAISAPSTPLLLPTEDNEAL-PVKDFVKHVADLHANHKFSKEFEILKESYE 872

  Fly   898 EFW----DLPL-----NHQEKPMVFGSQTKNRYKTILPNENSRVLLESESSELTSLLGEIKRTSS 953
            |..    |:.:     ||.:      :::||||..||..::|||.| |::|:.....|:
Zfish   873 EIQGCTADMGITTDSSNHPD------NKSKNRYINILAYDHSRVKL-SQNSDKDGKTGD------ 924

  Fly   954 VTASEDLPYINANYIKGPDYVSKCYVATQGPLPNTIFEFWLMIYQNTQRYIRRCVDGGSSSSPHV 1018
                    ||||||:.|.:. .|.|:|.||||..::.:||.||:
Zfish   925 --------YINANYVDGFNQ-PKAYIAAQGPLKGSLEDFWRMIW--------------------- 959

  Fly  1019 DREQILQQYFQKIVMLTNFTEANRQKCAVYFPIELNEIFAVAAKCEVFQLSAAARDYFDRYLTPT 1083
                  :|....|||:||..|..|:||..|:|:|..|.:.    |.:..|.
Zfish   960 ------EQNVGVIVMITNLVEKGRRKCDQYWPLENQEDYG----CFLVTLK-------------- 1000

  Fly  1084 FVPDTVVASSDAIDYEISGRHIGVESVKVTLEGDLLEALPAQGSFFLIKNVGIVR--RNGYSVRK 1146
                             |.|.:...:::.                |.::||.|.:  :.|.|..:
Zfish  1001 -----------------SSRTLAYYTLRT----------------FTLRNVQIKKGSQKGRSQER 1032

  Fly  1147 LVLLYCIRVPQSASYHLQKIYCYHYWYPDWPDHHSPRDINTLLDTCLHVLNLGKCESEFDIYDDT 1211
            .||                    |:.|..|||...|       :..|.:|:..:..|:
Zfish  1033 TVL--------------------HFHYTQWPDMGVP-------EYTLPLLSFIRTSSQ------- 1063

  Fly  1212 RSERNAHLAAQRLEIYQQDIFNAVQPLPVIHCSAGIGRTGCFTAILNAVRQLRQSLAYSLTGMLT 1276
              .|.|.:.                |: |:|||||:||||.:..|.:.::|:::.
Zfish  1064 --ARTAEMG----------------PV-VVHCSAGVGRTGTYIVIDSMLKQIKEE---------- 1099

  Fly  1277 KSLTSSSTEEYHNPTDSDSSFTCNTIRHISHILDHRDAEAVKTPPSFDRLPKMPDIFVDVLGIVC 1341
                                   ||                                |:::|.:.
Zfish  1100 -----------------------NT--------------------------------VNIMGFLK 1109

  Fly  1342 NLRLQRGGMVQNSEQYELIHRAI--CLYLKRTL 1372
            ::|.||..:||..|||..||.|:  .:..|.||
Zfish  1110 HIRTQRNYLVQTEEQYVFIHDALVEAIRSKETL 1142

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PTP-ER	NP_726092.1	PTP_DSP_cys	919..1362	CDD:475123	93/444 (21%)
ptprz1b	XP_073803012.1	None