Protein Alignment PTP-ER and ptpn18

DIOPT Version :9

• Sequence 1: NP_726092.1
• Gene: PTP-ER / 37461
• FlyBaseID: FBgn0016641
• Length: 1377
• Species: Drosophila melanogaster
• Sequence 2: NP_001013470.1
• Gene: ptpn18 / 541324
• ZFINID: ZDB-GENE-050320-12
• Length: 513
• Species: Danio rerio
• Alignment Length: 458
• Identity: 101/458 - (22%)
• Similarity: 146/458 - (31%)
• Gaps: 217/458 - (47%)

  Fly   918 KNRYKTILPNENSRVLLESESSELTSLLGEIKRTSSVTASEDLPYINANYIKGPDYVSKCYVATQ 982
            ||||:.|||.:.:||.|...:||..|                 .|||||::||. ..::.|:|||
Zfish    59 KNRYRDILPYDQTRVCLTPTTSEYQS-----------------DYINANFVKGA-VRNRTYIATQ 105

  Fly   983 GPLPNTIFEFWLMIYQNTQRYIRRCVDGGSSSSPHVDREQILQQYFQKIVMLTNFTEANRQKCAV 1047
            |||.:|:.:||.||:|:..:.                           |:|.....|..::||.|
Zfish   106 GPLSSTVVDFWRMIWQHNVKV---------------------------IIMACREIEMGKKKCEV 143

  Fly  1048 YFPIELNEIFAVAAKCEVFQLSAAARDYFDRYLTPTFVPDTVVASSDAIDYEISGRHIGVESVKV 1112
            |:                    |:..|      |.|..|.||                      .
Zfish   144 YW--------------------ASTSD------TSTLGPFTV----------------------S 160

  Fly  1113 TLEGDLLEALPAQGSFFLIKNVGIVRRNGYSVRKLVLLYCIRVPQSASYHLQKIYCYHYWYPDWP 1177
            |||    |:.|         |..::      ||.||:.||....:.:          |:.|..||
Zfish   161 TLE----ESRP---------NEEVI------VRTLVVNYCDEARKVS----------HFQYTAWP 196

  Fly  1178 DHHSPRDINTLLDTCLHVLNLGKCESEFDIYDDTRSERNAHLAAQRLEIYQQDIFNAVQPLPVIH 1242
            ||..|                       |:.|....         .:|:.:|...|...|: |||
Zfish   197 DHGIP-----------------------DMPDGILG---------MMELARQKQGNQTDPV-VIH 228

  Fly  1243 CSAGIGRTGCFTAILNAVRQLRQSLAYSLTGMLTKSLTSSSTEEYHNPTDSDSSFTCNTIRHISH 1307
            ||||.||||...|: :.|..|              .||....|::
Zfish   229 CSAGCGRTGVICAV-DYVNDL--------------LLTEQIQEDF-------------------- 258

  Fly  1308 ILDHRDAEAVKTPPSFDRLPKMPDIFVDVLGIVCNLRLQRGGMVQNSEQYELIHRAICLYLKRTL 1372
                                       ::|.:|..||.||...||..|||..:...:....::.|
Zfish   259 ---------------------------NILDLVLELRRQRPSAVQTKEQYGFVFHTVAQMFQKAL 296

  Fly  1373 ALR 1375
            .::
Zfish   297 EMK 299

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PTP-ER	NP_726092.1	Y_phosphatase	916..1364	CDD:278528	100/445 (22%)
		PTPc	917..1364	CDD:238006	100/445 (22%)
ptpn18	NP_001013470.1	Y_phosphatase	56..290	CDD:278528	100/447 (22%)
		PTPc	58..290	CDD:238006	100/447 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0789
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900