DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PTP-ER and B0280.17

DIOPT Version :9

Sequence 1:	NP_726092.1	Gene:	PTP-ER / 37461	FlyBaseID:	FBgn0016641	Length:	1377	Species:	Drosophila melanogaster
Sequence 2:	NP_001040836.2	Gene:	B0280.17 / 4363051	WormBaseID:	WBGene00044674	Length:	260	Species:	Caenorhabditis elegans

Alignment Length:	197	Identity:	41/197 - (20%)
Similarity:	71/197 - (36%)	Gaps:	63/197 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 TPRPTHAAPSDTTPLEAGEDAESN--------KSTP-YFTPLEYLQTSFEFPSPTVEVGGGVP-G 75
            ||.|:....::     ||:|...:        |..| ..||...||....|...|:.:.||:. |
Worm    66 TPPPSFLGRAN-----AGKDESMDLSSLRNLLKDDPLLMTPPPGLQRRQTFSPMTLSLIGGLKNG 125

  Fly    76 FPEHEDQEE-------EVFTPRQFTITSPHPAAHVHHPSSSQSPTLGRKFKRLSQYDR------- 126
            ..|:|::||       :||.|.: |..:.:|...:          :|.:...:.|.::
Worm   126 CSENENKEEGKFEKIDKVFFPPE-TANNTNPVGRL----------IGPRGMTIRQLEKDLGCKLF 179

  Fly   127 ---RSCSPHINTSSGEER-----------------VSGRGIDKENTMPKGGSVDQDLENSLYLSK 171
               :.|:   ...:.|||                 :|.|...:|....|..|:.:.|:..|..:.
Worm   180 IRGKGCT---KDDAKEERLRERVGWEHLKEPIHVMISVRSDSEEAASEKLSSIKKMLQEFLEHTD 241

  Fly   172 SE 173
            ||
Worm   242 SE 243

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PTP-ER	NP_726092.1	Y_phosphatase	916..1364	CDD:278528
PTP-ER	NP_726092.1	PTPc	917..1364	CDD:238006
B0280.17	NP_001040836.2	KH-I	141..260	CDD:381803	20/117 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0789
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900