Protein Alignment PTP-ER and Y71G12B.31

DIOPT Version :10

• Sequence 1: NP_726092.1
• Gene: PTP-ER / 37461
• FlyBaseID: FBgn0016641
• Length: 1377
• Species: Drosophila melanogaster
• Sequence 2: NP_001293450.1
• Gene: Y71G12B.31 / 3565511
• WormBaseID: WBGene00044348
• Length: 423
• Species: Caenorhabditis elegans
• Alignment Length: 613
• Identity: 123/613 - (20%)
• Similarity: 185/613 - (30%)
• Gaps: 281/613 - (45%)

  Fly   786 PLSP--QTTSEEFKIYLAS--------IQMLQSASNP-LNQFDLIRLNYVFDHSYQTNRNIIEQP 839
            |..|  :.|::|..:..|:        |...|..|.| ..:.|.:|::        ||:..
 Worm    57 PAPPPVEVTTKEIAVIAAAAAADGKNQINGFQKISTPAAKRPDKLRID--------TNKVC---- 109

  Fly   840 PVLGSNARDVETPTD-----MVPPSSEDSELLASYQTVVSRMAQPIPELKENEQKRIFRDLHKEF 899
            |...:.|.:.:...|     |...|:....||.....|:||          .|.:|:.|..
 Worm   110 PAQSAIAMETDYSADSFLASMTKESTNRRRLLQDEFLVLSR----------TEARRLTRST---- 160

  Fly   900 WDLPLNHQEKPMVFGSQTKNRYKTILPNENSRVLLESESSELTSLLGEIKRTSSVTASEDLPYIN 964
             |....|         ...|||..|:|.:::.|.|::         |:              |||
 Worm   161 -DRATRH---------AAANRYSDIVPYDHTLVELDT---------GD--------------YIN 192

  Fly   965 ANYIKGPDYVSKCYVATQGPLPN-------TIFEFWLMIYQNTQRYIRRCVDGGSSSSPHVDREQ 1022
            |::::|....:: ::|||||:.:       |:.:||.||.|    |...|
 Worm   193 ASFVQGESDATR-WIATQGPIDSGECIGKETVSDFWRMIVQ----YDVAC--------------- 237

  Fly  1023 ILQQYFQKIVMLTNFTEANRQKCAVYFPIELNEI-----FAVAAKCEVFQLSAAARDYFDRYLTP 1082
                    ||||....|...|||..|:|..:.:.     ..|...||:.:.:...|: ||  ::|
 Worm   238 --------IVMLGQHQEDFVQKCGEYWPSAMGKTERYGEVDVKLVCELEEKTWVHRE-FD--VSP 291

  Fly  1083 TFVPDTVVASSDAIDYEISGRHIGVESVKVTLEGDLLEALPAQGSFFLIKNVGIVRRNGYSVRKL 1147
            |        ||    |..|.:                                       |.||
 Worm   292 T--------SS----YSSSTK---------------------------------------SSRK- 304

  Fly  1148 VLLYCIRVPQSASYHLQKIYCYHYWYPDWPD-HHSPRDINTLLDTCLHVLNLGKCESEFDIYDDT 1211
                     ..||.....:....:.|.:|.| ..:||..|.|               ||
 Worm   305 ---------SRASRQQSHMKVSQWQYKEWKDTGGAPRIANFL---------------EF------ 339

  Fly  1212 RSERNAHLAAQRLEIYQQDIFNAVQPLPVIHCSAGIGRTGCFTAILNAVRQLRQSLAYSLTGMLT 1276
                   |...|...|...|        |:||||||||||.|..
 Worm   340 -------LLQVRGRQYTSPI--------VVHCSAGIGRTGVFIC--------------------- 368

  Fly  1277 KSLTSSSTEEYHNPTDSDSSFTCNTIRHISHILDHRDAEAVKTPPSFDRLPKMPDIFVDVLGIVC 1341
                          ||              :::...::|.:                :|:...|.
 Worm   369 --------------TD--------------NVISRFESEGI----------------IDIFSEVN 389

  Fly  1342 NLRLQRGGMVQNSEQYELIHRAICLYLK 1369
            ..|.||..||...:|||.|:..|..||:
 Worm   390 RSRQQRPSMVYTVKQYECIYDIIGEYLR 417

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PTP-ER	NP_726092.1	PTP_DSP_cys	919..1362	CDD:475123	92/455 (20%)
Y71G12B.31	NP_001293450.1	Y_phosphatase	170..412	CDD:459674	92/457 (20%)