Protein Alignment PTP-ER and Ptpn18

DIOPT Version :9

• Sequence 1: NP_726092.1
• Gene: PTP-ER / 37461
• FlyBaseID: FBgn0016641
• Length: 1377
• Species: Drosophila melanogaster
• Sequence 2: XP_038939136.1
• Gene: Ptpn18 / 301333
• RGDID: 1311586
• Length: 459
• Species: Rattus norvegicus
• Alignment Length: 528
• Identity: 102/528 - (19%)
• Similarity: 172/528 - (32%)
• Gaps: 254/528 - (48%)

  Fly   873 VSRMAQPIPELKENEQKRIFRD---LHKEFWDLPLNHQEKPMVF--------------GSQTKNR 920
            :||.:..:....|.::.|..|:   |.:||.|:    :.:.:.:              |:..|||
  Rat     1 MSRQSDLVRSFLEQQEARDHREGAILAREFSDI----KARSVAWKTEGVCSTKAGSQQGNSKKNR 61

  Fly   921 YKTILPNENSRVLLESESSELTSLLGEIKRTSSVTASEDLPYINANYIKGPDYVSKCYVATQGPL 985
            ||.::|.:.:||:|        |||.|.....         |||||:|:|.| .|:.|:||||||
  Rat    62 YKDVVPYDETRVIL--------SLLQEEGHGD---------YINANFIRGTD-GSQAYIATQGPL 108

  Fly   986 PNTIFEFWLMIYQNTQRYIRRCVDGGSSSSPHVDREQILQQYFQKIVMLT-NFTEANRQKCAVYF 1049
            |:|:.:||.:::                            ::..|::::. ..||..|:||..|:
  Rat   109 PHTLLDFWRLVW----------------------------EFGVKVILMACQETENGRRKCERYW 145

  Fly  1050 PIELNEI----FAVAAKCEVFQLSAAARDYFDRYLTPTFVPDTVVASSDAIDYEISGRHIGVESV 1110
            ..|...:    |.:                       |...:|.:.:.           |.:.::
  Rat   146 AQEREPLQAGPFCI-----------------------TLTKETALTAD-----------ITLRTL 176

  Fly  1111 KVTLEGDLLEALPAQGSFFLIKNVGIVRRNGYSVRKLVLLYCIRVPQSAS-----YHLQKIYCYH 1170
            :||.:                                      :||:...     :.||
  Rat   177 QVTFQ--------------------------------------KVPKGQKESRPVHQLQ------ 197

  Fly  1171 YWYPDWPDHHSPRDINTLLDTCLHVLNLGKCESEFDIYDDTRSERNAHLAAQRLEIYQQDIFNAV 1235
              |..||||..|...:       |:|.:                           :.:......:
  Rat   198 --YMSWPDHGVPSSSD-------HILTM---------------------------VEEARCLQGL 226

  Fly  1236 QPLPV-IHCSAGIGRTGCFTAILNAVRQLRQSLAYSLTGMLTKSLTSSSTEEYHNPTDSDSSFTC 1299
            .|.|: :|||||.||||...|: :.||||          :||:::
  Rat   227 GPGPLCVHCSAGCGRTGVLCAV-DYVRQL----------LLTQTI-------------------- 260

  Fly  1300 NTIRHISHILDHRDAEAVKTPPSFDRLPKMPDIFVDVLGIVCNLRLQRGGMVQNSEQYELIHRAI 1364
                                ||:|           .:..:|..:|.||...||..|||..::..:
  Rat   261 --------------------PPNF-----------SLFEVVLEMRKQRPAAVQTEEQYRFLYHTV 294

  Fly  1365 CLYLKRTL 1372
            .....|||
  Rat   295 AQLFSRTL 302

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PTP-ER	NP_726092.1	Y_phosphatase	916..1364	CDD:278528	89/458 (19%)
		PTPc	917..1364	CDD:238006	89/457 (19%)
Ptpn18	XP_038939136.1	PTP_DSP_cys	27..298	CDD:421693	93/496 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0789
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900