Protein Alignment PTP-ER and Ptpn22

DIOPT Version :9

• Sequence 1: NP_726092.1
• Gene: PTP-ER / 37461
• FlyBaseID: FBgn0016641
• Length: 1377
• Species: Drosophila melanogaster
• Sequence 2: NP_001099930.1
• Gene: Ptpn22 / 295338
• RGDID: 1307992
• Length: 804
• Species: Rattus norvegicus
• Alignment Length: 502
• Identity: 110/502 - (21%)
• Similarity: 161/502 - (32%)
• Gaps: 234/502 - (46%)

  Fly   883 LKENEQKRIFR-DLHKEFWDL-------------PLNHQEKPMVFGSQTKNRYKTILPNENSRVL 933
            |||.::|:|.| :...||..|             |....::|.   :..|||||.|||.::|.|.
  Rat    11 LKEAQKKKINREEFANEFLKLKRQSTKYKADKIYPTTVAQRPK---NIKKNRYKDILPYDHSLVE 72

  Fly   934 LESESSELTSLLGEIKRTSSVTASEDLPYINANYIKGPDYVSKCYVATQGPLPNTIFEFWLMIYQ 998
            |                 |.:|:.||..||||::|||. |..:.|:||||||..|:.:||.||::
  Rat    73 L-----------------SLLTSDEDSSYINASFIKGV-YGPRAYIATQGPLSTTLLDFWRMIWE 119

  Fly   999 NTQRYIRRCVDGGSSSSPHVDREQILQQYFQKIVMLTNFTEANRQKCAVYFPIELNEIFAVAAKC 1063
                                  .::|     .|||.....|..::||..|:
  Rat   120 ----------------------YRVL-----VIVMACMEFEMGKKKCERYW-------------- 143

  Fly  1064 EVFQLSAAARDYFDRYLTPTFVPDTVVASSDAIDYEISGRHIGVESVKVTLEGDLLEALPAQGSF 1128
                                       |.......:.....|..|:.|
  Rat   144 ---------------------------AEPGETQLQFGPFSISCETEK----------------- 164

  Fly  1129 FLIKNVGIVRRNGYSVRKLVLLYCIRVPQSASYHLQKIYCYHYWYPDWPDHHSPRDINTLLDTCL 1193
                     :::.|.:|.|          .|.::.:....|.:.|.:||||..|..|:.:|..
  Rat   165 ---------KKSDYKIRTL----------KAKFNSETRIVYQFHYKNWPDHDVPSSIDPILQL-- 208

  Fly  1194 HVLNLGKCESEFDIYDDTRSERNAHLAAQRLEIYQQDIFNAVQPLPVIHCSAGIGRTGCFTAILN 1258
                         |:|              :..||:|  :.| || .||||||.||||...|:
  Rat   209 -------------IWD--------------MRCYQED--DCV-PL-CIHCSAGCGRTGVICAV-- 240

  Fly  1259 AVRQLRQSLAYSLTGMLTKSLTSSSTEEYHNPTDSDSSFTCNTIRHISHILDHRDAEAVKTPPSF 1323
                       ..|.||.|.
  Rat   241 -----------DYTWMLLKD--------------------------------------------- 249

  Fly  1324 DRLPKMPDIFVDVLGIVCNLRLQRGGMVQNSEQYELIHRAICLYLKR 1370
            ..:||...:|    .::..:|.||..:||..|||||::.|:....||
  Rat   250 GIIPKNFSVF----NLIQEMRTQRPSLVQTQEQYELVYSAVLELFKR 292

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PTP-ER	NP_726092.1	Y_phosphatase	916..1364	CDD:278528	96/447 (21%)
		PTPc	917..1364	CDD:238006	96/446 (22%)
Ptpn22	NP_001099930.1	PTPc	24..288	CDD:214550	102/483 (21%)
		PTPc	56..288	CDD:238006	97/448 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0789
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900