Protein Alignment PTP-ER and pyp1

DIOPT Version :10

• Sequence 1: NP_726092.1
• Gene: PTP-ER / 37461
• FlyBaseID: FBgn0016641
• Length: 1377
• Species: Drosophila melanogaster
• Sequence 2: NP_594885.1
• Gene: pyp1 / 2542677
• PomBaseID: SPAC26F1.10C
• Length: 550
• Species: Schizosaccharomyces pombe
• Alignment Length: 644
• Identity: 126/644 - (19%)
• Similarity: 211/644 - (32%)
• Gaps: 288/644 - (44%)

  Fly   779 VRNIMTRPLSPQTTSEEFKIYLASIQMLQSASNPLNQFDLIRLNYVFDHSYQTNR--NIIEQPPV 841
            :.|.:|   :.:...|:|:        .:|.|......||       |:|..:.:  ::|:..||
pombe   123 IANYVT---NAEVIGEKFR--------KESYSGDFGILDL-------DYSKVSGKYPSVIDNSPV 169

  Fly   842 ---LGS--NARD----VETPTDMVPPSSEDSELLASYQTV-------VSRMAQPIPELKENEQKR 890
               ||:  :||.    ....|..:..|||.|:..:.....       ::....|:||.|:|:...
pombe   170 KSKLGALPSARPRLSYSAAQTAPISLSSEGSDYFSRPPPTPNVAGLSLNNFFCPLPENKDNKSSP 234

  Fly   891 I---------------------FRDLHKEFWDL-PLNHQE--------------KPMVFGSQTKN 919
            .                     ...|:::|..| .|.||.              ..:...|..||
pombe   235 FGSATVQTPCLHSVPDAFTNPDVATLYQKFLRLQSLEHQRLVSCSDRNSQWSTVDSLSNTSYKKN 299

  Fly   920 RYKTILPNENSRVLLESESSELTSLLGEIKRTSSVTASEDLPYINANYIKGPDYVSKCYVATQGP 984
            ||..|:|...:||              .:||||    ..:|.||||::||..   :..|:|.||.
pombe   300 RYTDIVPYNCTRV--------------HLKRTS----PSELDYINASFIKTE---TSNYIACQGS 343

  Fly   985 LPNTIFEFWLMIYQNTQRYIRRCVDGGSSSSPHVDREQILQQYFQKIVMLTNFTEANRQKCAVYF 1049
            :..:|.:||.|::.|.:.                         ...||||.:..||.|:.|..|:
pombe   344 ISRSISDFWHMVWDNVEN-------------------------IGTIVMLGSLFEAGREMCTAYW 383

  Fly  1050 PIELNEIFAVAAKCEVFQLSAAARDYFDRYLTPTFVPDTVVASSDAIDYEISG----RHIGVESV 1110
            |                                         |:...|.::.|    :.|..|:|
pombe   384 P-----------------------------------------SNGIGDKQVYGDYCVKQISEENV 407

  Fly  1111 KVTLEGDLLEALPAQGSFFLIKNVGIVRRNGYSVRKLVLLYCIRVPQSASYHLQKIYCYHYWYPD 1175
                          ..|.|:::...|...|..||:|:                     :||.||:
pombe   408 --------------DNSRFILRKFEIQNANFPSVKKV---------------------HHYQYPN 437

  Fly  1176 WPDHHSPRDINTLLDTCLHVLNLGKCESEFDIYDDTRSERNAHLAAQRLEIYQQDIFNAVQPLPV 1240
            |.|.:||.::.::::...:|                   .|:|.:..                .:
pombe   438 WSDCNSPENVKSMVEFLKYV-------------------NNSHGSGN----------------TI 467

  Fly  1241 IHCSAGIGRTGCFTAILNAVRQLRQSLAYSLTGMLTKSLTSSSTEEYHNPTDSDSSFTCNTIRHI 1305
            :|||||:||||.| .:|:.:.:..:|   .|:|.              ||:.:|||
pombe   468 VHCSAGVGRTGTF-IVLDTILRFPES---KLSGF--------------NPSVADSS--------- 505

  Fly  1306 SHILDHRDAEAVKTPPSFDRLPKMPDIFVDVLGIVCNLRLQRGGMVQNSEQYELIHRAI 1364
                                     |:   |..:|.::|.||..|||...|::.::..|
pombe   506 -------------------------DV---VFQLVDHIRKQRMKMVQTFTQFKYVYDLI 536

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PTP-ER	NP_726092.1	PTP_DSP_cys	919..1362	CDD:475123	90/446 (20%)
pyp1	NP_594885.1	RHOD	41..161	CDD:444705	10/55 (18%)
		PTPc	271..536	CDD:214550	94/476 (20%)