Protein Alignment PTP-ER and Ptpn20

DIOPT Version :9

• Sequence 1: NP_726092.1
• Gene: PTP-ER / 37461
• FlyBaseID: FBgn0016641
• Length: 1377
• Species: Drosophila melanogaster
• Sequence 2: XP_006518791.1
• Gene: Ptpn20 / 19256
• MGIID: 1196295
• Length: 463
• Species: Mus musculus
• Alignment Length: 581
• Identity: 125/581 - (21%)
• Similarity: 191/581 - (32%)
• Gaps: 270/581 - (46%)

  Fly   824 VFDHSYQTNRNIIEQ---------PPVLGSNAR---DVETPTDMVPPSSEDSEL--LASYQTVV- 873
            |.|.|.:...|.::.         .|||..::|   |.||       |..:.||  ||..:.::
Mouse   122 VSDRSLRNRWNSMDSETAGPSKTVSPVLSGSSRLSKDTET-------SVSEKELTQLAQIRPLIF 179

  Fly   874 -----SRMAQPIPELKENEQKRIFRDLHKEFWDLPLNHQEKPMVFGS------QTKNRYKTILPN 927
                 |.|...:..|::.|:..|.|:.      |.|.....|..|.|      :.||||:.|||.
Mouse   180 NSSARSAMRDCLNTLQKKEELDIIREF------LELEQMTLPDDFNSGNTLQNRDKNRYRDILPY 238

  Fly   928 ENSRVLLESESSELTSLLGEIKRTSSVTASEDLPYINANYIKGPDYVSK-CYVATQGPLPNTIFE 991
            :::||.|                      .::..||||:||:..::..: .|:|||||||.||.:
Mouse   239 DSTRVPL----------------------GKNKDYINASYIRIVNHEEEYFYIATQGPLPETIED 281

  Fly   992 FWLMIYQNTQRYIRRCVDGGSSSSPHVDREQILQQYFQKIVMLTNFTEANRQKCAVYFPIELNEI 1056
            ||.|:.:|      .|                     ..|.|:|...|....||..|:||.|.|
Mouse   282 FWQMVLEN------NC---------------------NVIAMITREIECGVIKCYSYWPISLKE- 318

  Fly  1057 FAVAAKCEVFQLSAAARDYFDRYLTPTFVPDTVVASSDAIDYEISGRHIGV--ESVKVTLEGDLL 1119
                                                  .:::|    |..|  |:..||
Mouse   319 --------------------------------------PLEFE----HFSVFLETFHVT------ 335

  Fly  1120 EALPAQGSFFLIKNVGIVRRN-GYSVRKLVLLYCIRVPQSASYHLQKIYCYHYWYPDWPDHHSPR 1183
                   .:|.::...||::: |.|       .|::       |||        :..||||.:|.
Mouse   336 -------QYFTVRVFQIVKKSTGKS-------QCVK-------HLQ--------FTKWPDHGTPA 371

  Fly  1184 DINTLLDTCLHVLNLGKCESEFDIYDDTRSERNAHLAAQRLEIYQQDIFNAVQPLPVIHCSAGIG 1248
            ..:..:....:|                   |.:|:..               || ::|||||:|
Mouse   372 SADFFIKYVRYV-------------------RKSHITG---------------PL-LVHCSAGVG 401

  Fly  1249 RTGCFTAILNAVRQLRQSLAYSLTGMLTKSLTSSSTEEYHNPTDSDSSFTCNTIRHISHILDHRD 1313
            |||.|..:                                     |..|:
Mouse   402 RTGVFICV-------------------------------------DVVFS--------------- 414

  Fly  1314 AEAVKTPPSFDRLPKMPDIFVDVLGIVCNLRLQRGGMVQNSEQYELIHRAICLYLKRTLAL 1374
              |::...||           |::.||..:|.||.||:|..|||:..:..:...|:..|||
Mouse   415 --AIEKNYSF-----------DIMNIVTQMRKQRCGMIQTKEQYQFCYEIVLEVLQNLLAL 462

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PTP-ER	NP_726092.1	Y_phosphatase	916..1364	CDD:278528	94/451 (21%)
		PTPc	917..1364	CDD:238006	94/450 (21%)
Ptpn20	XP_006518791.1	PTP_DSP_cys	251..457	CDD:391942	84/410 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0789
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900