Protein Alignment PTP-ER and Ptpn12

DIOPT Version :10

• Sequence 1: NP_726092.1
• Gene: PTP-ER / 37461
• FlyBaseID: FBgn0016641
• Length: 1377
• Species: Drosophila melanogaster
• Sequence 2: NP_001343519.1
• Gene: Ptpn12 / 19248
• MGIID: 104673
• Length: 789
• Species: Mus musculus
• Alignment Length: 458
• Identity: 110/458 - (24%)
• Similarity: 157/458 - (34%)
• Gaps: 219/458 - (47%)

  Fly   918 KNRYKTILPNENSRVLLESESSELTSLLGEIKRTSSVTASEDLPYINANYIKGPDYVSKCYVATQ 982
            |||||.|||.::|||.|..:                 |.|:|..|||||:|||. |..|.|||||
Mouse    75 KNRYKDILPFDHSRVKLTLK-----------------TPSQDSDYINANFIKGV-YGPKAYVATQ 121

  Fly   983 GPLPNTIFEFWLMIYQNTQRYIRRCVDGGSSSSPHVDREQILQQYFQKIVMLTNFTEANRQKCAV 1047
            |||.||:.:||.||::..                           ...|||.....|..|:||..
Mouse   122 GPLANTVIDFWRMIWEYN---------------------------VVIIVMACREFEMGRKKCER 159

  Fly  1048 YFPIELNEIFAVAAKCEVFQLSAAARDYFDRYLTPTFVPDTVVASSDAIDYEISGRHIGVESVKV 1112
            |:|:                       |.:..:  ||.|                       .|:
Mouse   160 YWPL-----------------------YGEDPI--TFAP-----------------------FKI 176

  Fly  1113 TLEGDLLEALPAQGSFFLIKNVGIVRRNGYSVRKLVLLYCIRVPQSASYHLQKIYCYHYWYPDWP 1177
            :.|.:                   ..|..|.:|.|:|.:     |:.|   :::|.:|  |.:||
Mouse   177 SCENE-------------------QARTDYFIRTLLLEF-----QNES---RRLYQFH--YVNWP 212

  Fly  1178 DHHSPRDINTLLDTCLHVLNLGKCESEFDIYDDTRSERNAHLAAQRLEIYQQDIFNAVQPLPV-I 1241
            ||..|...:::||    :::|                         :..||:.     :.:|: |
Mouse   213 DHDVPSSFDSILD----MISL-------------------------MRKYQEH-----EDVPICI 243

  Fly  1242 HCSAGIGRTGCFTAILNAVRQLRQSLAYSLTGMLTKSLTSSSTEEYHNPTDSDSSFTCNTIRHIS 1306
            |||||.||||...||                                       .:|.|.::
Mouse   244 HCSAGCGRTGAICAI---------------------------------------DYTWNLLK--- 266

  Fly  1307 HILDHRDAEAVKTPPSFDRLPKMPDIFVDVLGIVCNLRLQRGGMVQNSEQYELIHRAICLYLKRT 1371
                     |.|.|..|           :|..::..:|.||...||..|||||:||||....::.
Mouse   267 ---------AGKIPEEF-----------NVFNLIQEMRTQRHSAVQTKEQYELVHRAIAQLFEKQ 311

  Fly  1372 LAL 1374
            |.|
Mouse   312 LQL 314

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PTP-ER	NP_726092.1	PTP_DSP_cys	919..1362	CDD:475123	103/443 (23%)
Ptpn12	NP_001343519.1	PTP_DSP_cys	43..312	CDD:475123	108/454 (24%)