Protein Alignment PTP-ER and Ptpn1

DIOPT Version :9

• Sequence 1: NP_726092.1
• Gene: PTP-ER / 37461
• FlyBaseID: FBgn0016641
• Length: 1377
• Species: Drosophila melanogaster
• Sequence 2: NP_035331.3
• Gene: Ptpn1 / 19246
• MGIID: 97805
• Length: 432
• Species: Mus musculus
• Alignment Length: 478
• Identity: 88/478 - (18%)
• Similarity: 146/478 - (30%)
• Gaps: 226/478 - (47%)

  Fly   891 IFRDLHKEFWDLPLNHQEKPMVFGSQTKNRYKTILPNENSRVLLESESSELTSLLGEIKRTSSVT 955
            |::|:..|..|.|....:.|.   ::.:|||:.:.|.::||:.|..|.::
Mouse    19 IYQDIRHEASDFPCKVAKLPK---NKNRNRYRDVSPFDHSRIKLHQEDND--------------- 65

  Fly   956 ASEDLPYINANYIKGPDYVSKCYVATQGPLPNTIFEFWLMIYQNTQRYIRRCVDGGSSSSPHVDR 1020
                  ||||:.|| .:...:.|:.||||||||...||.|:::...|
Mouse    66 ------YINASLIK-MEEAQRSYILTQGPLPNTCGHFWEMVWEQKSR------------------ 105

  Fly  1021 EQILQQYFQKIVMLTNFTEANRQKCAVYFPIELNEIFAVAAKCEVFQLSAAARDYFDRYLTPTFV 1085
                     .:|||....|....|||.|:|.:..:...                 ||
Mouse   106 ---------GVVMLNRIMEKGSLKCAQYWPQQEEKEMV-----------------FD-------- 136

  Fly  1086 PDTVVASSDAIDYEISGRHIGVESVKVTLEGDLLEALPAQGSFFLIKNVGIVRRNGYSVRKLVLL 1150
             ||                    .:|:||..:.::      |::.::.:.:........|:::
Mouse   137 -DT--------------------GLKLTLISEDVK------SYYTVRQLELENLTTKETREIL-- 172

  Fly  1151 YCIRVPQSASYHLQKIYCYHYWYPDWPDHHSPRDINTLLDTCLHVLNLGKCESEFDIYDDTRSER 1215
                               |:.|..|||...|....:.|:....|...|....|..
Mouse   173 -------------------HFHYTTWPDFGVPESPASFLNFLFKVRESGSLSLEHG--------- 209

  Fly  1216 NAHLAAQRLEIYQQDIFNAVQPLPVIHCSAGIGRTGCF----TAILNAVRQLRQSLAYSLTGMLT 1276
                                 |: |:||||||||:|.|    |.:|
Mouse   210 ---------------------PI-VVHCSAGIGRSGTFCLADTCLL------------------- 233

  Fly  1277 KSLTSSSTEEYHNPTDSDSSFTCNTIRHISHILDHRDAEAVKTPPSFDRLPKMPDIFVDVLGIVC 1341
                                           ::|.|     |.|.|           ||:..::.
Mouse   234 -------------------------------LMDKR-----KDPSS-----------VDIKKVLL 251

  Fly  1342 NLRLQRGGMVQNSEQYELIHRAI 1364
            .:|..|.|::|.::|....:.|:
Mouse   252 EMRRFRMGLIQTADQLRFSYLAV 274

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PTP-ER	NP_726092.1	Y_phosphatase	916..1364	CDD:278528	81/451 (18%)
		PTPc	917..1364	CDD:238006	81/450 (18%)
Ptpn1	NP_035331.3	PTPc	3..276	CDD:214550	88/478 (18%)
		PTPc	43..276	CDD:238006	82/451 (18%)
		Substrate binding. /evidence=ECO:0000250	215..221		5/5 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	297..322
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	335..399

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0789
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900