Protein Alignment PTP-ER and T27A3.5

DIOPT Version :9

• Sequence 1: NP_726092.1
• Gene: PTP-ER / 37461
• FlyBaseID: FBgn0016641
• Length: 1377
• Species: Drosophila melanogaster
• Sequence 2: NP_491761.3
• Gene: T27A3.5 / 188965
• WormBaseID: WBGene00020841
• Length: 355
• Species: Caenorhabditis elegans
• Alignment Length: 549
• Identity: 110/549 - (20%)
• Similarity: 166/549 - (30%)
• Gaps: 261/549 - (47%)

  Fly   845 NARDVETPTDMVPPSSED-------SELLASYQTVVSRMAQPIPELKENEQKRIFRD-------- 894
            |||..:.||..:...:||       .:..|..::.|.|.|....::.|    .|.||
 Worm     9 NARKNQEPTSNMTIETEDGTQADRPKKRPAKKRSKVVRRAAQYGDVNE----PILRDFVKATIQT 69

  Fly   895 ----LHKEFWDLPLNHQ--EKPMV--FGSQTKNRYKTILPNENSRVLLESESSELTSLLGEIKRT 951
                |..||.:|.:..|  .||..  .|...|||||.:...:::||:|:
 Worm    70 GVKQLSTEFLNLKMETQPCNKPKTGHEGHPEKNRYKDVYCIDDTRVVLK---------------- 118

  Fly   952 SSVTASEDLP--YINANYIK--GPDYVSKCYVATQGPLPNTIFEFWLMIYQNTQRYIRRCVDGGS 1012
                ..||.|  ||:||::|  |    :..::.||||...|:.:|:.:|:|
 Worm   119 ----WPEDSPSDYIHANWVKING----ANKFICTQGPTEKTVDDFYRLIWQ-------------- 161

  Fly  1013 SSSPHVDREQILQQYFQKIVMLTNFTEANRQKCAVYFPIELNEIFAVAAKCEVFQLSAAARDYFD 1077
            ..:|.|             |||.|..|..::||..|:
 Worm   162 EKAPCV-------------VMLCNIMECGKKKCEQYW---------------------------- 185

  Fly  1078 RYLTPTFVPDTVVASSDAIDYEISGRHIGVESVKVTLEGDLLEALPAQGSFFLIKNVGIVRRNGY 1142
                    |:|.......:|        |..:||:        |.||:
 Worm   186 --------PETADGQMILMD--------GKLTVKI--------AEPAK----------------- 209

  Fly  1143 SVRKLVLLYCIRV--PQSASYHLQKIYCYHYWYPDWPDHHSPRDINTLLDTCLHVLNLGKCESEF 1205
            .|.:.:||..|.|  .:..|::.:     |:.:..|||...|
 Worm   210 EVEQNILLMKITVIDDKGTSHNFE-----HWQWKAWPDRGVP----------------------- 246

  Fly  1206 DIYDDTRSERNAHLAAQRLEIYQQDIFNAVQPLPVIHCSAGIGRTGCFTAILNAVRQLRQSLAYS 1270
                      ...:|..||.|.    .....|: |:||||||||||                  |
 Worm   247 ----------ELPMAVFRLLIR----LKTASPI-VVHCSAGIGRTG------------------S 278

  Fly  1271 LTGMLTKSLTSSSTEEYHNPTDSDSSFTCNTIRHISHILDHRDAEAVKTPPSFDRLPKMPDIFVD 1335
            :.|:....:...:.|:                                               |.
 Worm   279 IVGLEIALVKFCAGEK-----------------------------------------------VV 296

  Fly  1336 VLGIVCNLRLQRGGMVQNSEQYELIHRAI 1364
            :..||..:|.||.|.||...||..:||.:
 Worm   297 LKDIVKEIRNQRHGSVQTDAQYLFMHRVL 325

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PTP-ER	NP_726092.1	Y_phosphatase	916..1364	CDD:278528	87/453 (19%)
		PTPc	917..1364	CDD:238006	87/452 (19%)
T27A3.5	NP_491761.3	PTPc	73..326	CDD:214550	95/481 (20%)
		PTPc	100..326	CDD:238006	87/454 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0789
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900