Protein Alignment PTP-ER and F36H1.3

DIOPT Version :9

• Sequence 1: NP_726092.1
• Gene: PTP-ER / 37461
• FlyBaseID: FBgn0016641
• Length: 1377
• Species: Drosophila melanogaster
• Sequence 2: NP_502058.3
• Gene: F36H1.3 / 185379
• WormBaseID: WBGene00009492
• Length: 532
• Species: Caenorhabditis elegans
• Alignment Length: 643
• Identity: 123/643 - (19%)
• Similarity: 202/643 - (31%)
• Gaps: 282/643 - (43%)

  Fly   733 NSSKANSQKFFGQVCFGSASDLQPNPQQDSVREDQAIGATCTCAGTVRNIMTRPLSPQTTSEEFK 797
            |..|:||:.          ::.:.|.||.|.::.::....|:......|...:....:.::.|.|
 Worm     9 NRKKSNSKD----------TNKKKNKQQASAKKKKSGDKNCSKRSKKHNTKQKSKREKKSAREKK 63

  Fly   798 IYLASIQMLQSA-SNPLNQ-FDLIRLNYVFDHSYQTNRNIIEQPPVLGSNARDVETPTDMVPPSS 860
                |::..:|| .|.::. ||.....:..:|..        .|..|  |...|:|
 Worm    64 ----SLREKKSARENTMHDIFDRDTFAFRLEHCV--------HPDAL--NRHSVQT--------- 105

  Fly   861 EDSELLASYQTVVSRMAQPIPELKENEQKRIFRDLHKEFWD-----LPLNHQEKPMVFGSQT--- 917
               |...::.|.|:.|.              ...|.||:.:     ||:.:.|: .:|...|
 Worm   106 ---EAFETFTTTVTSMG--------------VDGLAKEYLETLVPFLPVGYFER-SIFDKNTEFK 152

  Fly   918 KNRYKTILPNENSRVLLESESSELTSLLGEIKRTSSVTASEDLP--YINANYIKGPDYVSKCYVA 980
            |||||.:..|:.:||:|:                      :..|  |::|||:||   ....::.
 Worm   153 KNRYKDVPCNDKTRVILK----------------------DGYPGDYVHANYVKG---TKPMFIL 192

  Fly   981 TQGPLPNTIFEFWLMIYQNTQRYIRRCVDGGSSSSPHVDREQILQQYFQKIVMLTNFTEANRQKC 1045
            |||||.:|..:.|.|                           :||:....|.||....|..|.||
 Worm   193 TQGPLKDTAMDIWRM---------------------------VLQEGVAAICMLCELIENGRPKC 230

  Fly  1046 AVYFPIELNEIFA---VAAKCEVFQLSAAARDYFDRYLTPTFVPDTVVASSDAIDYEISGRHIGV 1107
            ..|||....::..   :...|                 |.:..||               .|..:
 Worm   231 EPYFPDTEGQVLTFGEITVTC-----------------TESTTPD---------------NHTQL 263

  Fly  1108 ESVKVTLEGDLLEALPAQGSFFLIKNVGIVRRNGYSVRKLVLLYCIRVPQSASYHLQKIYCYHYW 1172
            :.:.|                       :.:::|.| .||                     |||.
 Worm   264 KMLTV-----------------------MDKKSGKS-HKL---------------------YHYK 283

  Fly  1173 YPDWPDHHSPRDINTLLDTCLHVLNLGKCESEFDIYDDTRSERNAHLAAQRLEIYQQDIFNAVQP 1237
            ...|||                                 :|...::||..|       ...:::.
 Worm   284 IITWPD---------------------------------KSIALSNLAILR-------TLRSLRK 308

  Fly  1238 LP---VIHCSAGIGRTGCFTAI--------------------------LNAVRQLRQSLAYSLTG 1273
            :|   |:||||||||||.|.||                          ||:|:...|.|
 Worm   309 MPGPIVVHCSAGIGRTGTFAAIEVGAQCLLNGKAFRPADLVRAVRHCRLNSVQMDTQYL------ 367

  Fly  1274 MLTKSLTSSST--EEYHNPTDSDSSFTCNTIRHISHILDHRDA-----EAVKTPPSFD 1324
            ||.:::.....  :...:|...|:..|     :..::.|:.:|     |..|.||..:
 Worm   368 MLVEAILDLGVAFKYIEDPKSLDAIET-----YKRNVADYVEAHPPPLEMFKAPPKVE 420

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PTP-ER	NP_726092.1	Y_phosphatase	916..1364	CDD:278528	88/453 (19%)
		PTPc	917..1364	CDD:238006	88/452 (19%)
F36H1.3	NP_502058.3	PTPc	122..375	CDD:214550	86/428 (20%)
		PTPc	152..375	CDD:238006	78/397 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0789
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900