Protein Alignment PTP-ER and F35C11.2

DIOPT Version :10

• Sequence 1: NP_726092.1
• Gene: PTP-ER / 37461
• FlyBaseID: FBgn0016641
• Length: 1377
• Species: Drosophila melanogaster
• Sequence 2: NP_495736.1
• Gene: F35C11.2 / 185271
• WormBaseID: WBGene00009401
• Length: 397
• Species: Caenorhabditis elegans
• Alignment Length: 369
• Identity: 73/369 - (19%)
• Similarity: 122/369 - (33%)
• Gaps: 121/369 - (32%)

  Fly   728 STENLNSSKANSQKFFGQVCFGSASDLQPNPQQDSVREDQAIGATCTCAGTVRNIM-TRPLSPQT 791
            |...|..:::.:.:..|:...|...::..|     |..::|..|.......:.|.| |..::...
 Worm    23 SIRQLAGTESQTTQTGGETAEGKEEEVNKN-----VTPEEAFKAVTVEGPELLNQMHTSAMTYPN 82

  Fly   792 TSEEFKIYLASIQMLQSASNPLNQFDLIRLN--YVFDHSYQTNRNIIEQPPVLGSNARDVETPTD 854
            |.::|                ||..|:.|:.  |.||||                       ..:
 Worm    83 TYDKF----------------LNNMDMNRIPHLYCFDHS-----------------------RVE 108

  Fly   855 MVPPSSEDSELLASYQTVVSRMAQPI----PELKENEQKRIFRDLHKE--FWDLPLNHQEKP--- 910
            :.|...:|....||:....|:.:..|    |          |.| |.|  ||.:.  .:.||
 Worm   109 LAPQDGKDDFYNASWVDGYSKKSAYIFAQAP----------FND-HTEYVFWRMV--SERKPSMI 160

  Fly   911 MVFG-----SQTKNRY--------KTILPNENSRVLLESESSELTSLLGEIKRT--SSVTASEDL 960
            :|||     .:.|..|        |:.|....::.|.|.|      |..:|.|.  ....:.:|.
 Worm   161 LVFGDIDEKQKRKAPYDISDRGFEKSFLHEFGAKSLEECE------LKAKICRKFWPEKGSKKDF 219

  Fly   961 PYINANYIKGPDYVSKCYVATQGPLPNTIFEFWLMI------YQNTQRYIRRCVDGGSSSSPHVD 1019
            |.::   |:..|..|:.::.|          |.|.:      :|....:.....|........:|
 Worm   220 PALS---IQASDDHSETHMKT----------FNLTVTEKKQDHQTVLMHFYEWADASKLPEYMLD 271

  Fly  1020 -REQILQQYFQKI---------VMLTNFTEANRQKCAVYFPIEL 1053
             |..|..||.:..         :||...|..  :|||:|..|::
 Worm   272 MRASIKLQYIRSSKKTGVCIGPIMLVCATGV--EKCAIYATIDI 313

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PTP-ER	NP_726092.1	PTP_DSP_cys	919..1362	CDD:475123	32/161 (20%)
F35C11.2	NP_495736.1	PTPc	83..356	CDD:214550	62/304 (20%)