Protein Alignment PTP-ER and F40G12.10

DIOPT Version :10

• Sequence 1: NP_726092.1
• Gene: PTP-ER / 37461
• FlyBaseID: FBgn0016641
• Length: 1377
• Species: Drosophila melanogaster
• Sequence 2: NP_506537.1
• Gene: F40G12.10 / 179927
• WormBaseID: WBGene00009605
• Length: 438
• Species: Caenorhabditis elegans
• Alignment Length: 533
• Identity: 80/533 - (15%)
• Similarity: 158/533 - (29%)
• Gaps: 195/533 - (36%)

  Fly   828 SYQTNRNIIEQPPVLGSNARDVETPTDMVPPSSEDSELLASYQTVVSR--MAQPIPELKENEQKR 890
            |.:....:..:|....||::...|......|:...|::..::..:.::  .::...:||:.:::
 Worm    30 SKERGSELSRRPQKSRSNSKQKATGPTSALPTDPKSKIDTTFMEITAKGFKSKKGKKLKKKKEE- 93

  Fly   891 IFRDLHKEFWDLPLNHQEKPMVFGSQTKNRYK------TILPNENSRVLLESESSELTSLLGEI- 948
              ....|....|.|...|..|.|....||..|      .:|...:.|..:|.|...:.::..::
 Worm    94 --TSASKSPSTLTLGKAESHMDFSGNVKNVEKGVKVWIELLEKMDFRKTMEPEFKPIDTMKADLE 156

  Fly   949 -----KRTSSVTASEDLPYINANYIKG---------------PDYVSKCYVATQGPL---PNTIF 990
                 |:....:.||::...:.|.:||               |...:|..:..|..:   |.::.
 Worm   157 KCQAFKKNIDFSQSENVELYDTNRVKGGGEADFFYHGSTLTIPSVTTKSTILAQLAIVDSPQSLE 221

  Fly   991 EFWLMIYQNTQRYIRRCVDGGSSSSPHVDREQILQQYFQKIVMLTNFTEANRQKCAVYFPIELNE 1055
            .||:|                           :..|..|::.:|....|.::...:.|||.:..|
 Worm   222 SFWIM---------------------------VASQKIQRLFILLGEEELDKPTLSEYFPEDFKE 259

  Fly  1056 IFAVAAKCEVFQLSAAARDYFDRYLTPTFVPDTVVASSDAIDYEISGRHIGVESVKVTLEGDLLE 1120
            ...:                  |......||.|...::..:.||:..:..
 Worm   260 FKTI------------------RVNNRKTVPKTEEQANTQLYYEVVPKDC--------------- 291

  Fly  1121 ALPAQGSFFLIKNVGIVRRNGYSVRKLVLLYCIRVPQSASYHLQKIYCYHYWYPDWPDHHSPRDI 1185
               |:..|.:|:....                                       |||...|
 Worm   292 ---AEAPFAMIEICDF---------------------------------------WPDAKIP--- 311

  Fly  1186 NTLLDTCLHVLNLGKCESEFDIYDDTRSERNAHLAAQRLEIYQQDIFNAVQPLPVIHCSA----- 1245
                       .:|        |:        .:||....:::.|          |.|.|
 Worm   312 -----------TMG--------YN--------RIAATAASVFESD----------IDCDASCAIV 339

  Fly  1246 ---GIGRTGCFTAILNAVRQLRQSLAYSLTGMLTKSLTSSSTEEYHNPTDSDSSFTCNTIRHISH 1307
               |.||.|.|...:.|:.:|:...|.::     |.:..|...:.....::.|.:....:..:::
 Worm   340 SNYGAGRAGSFFVAVLAIEKLQAGEAPNI-----KEIALSVRSQRPAAIETLSQYMFTYVIALTY 399

  Fly  1308 ILDHRDAEAVKTP 1320
            .|.|     ||.|
 Worm   400 GLKH-----VKDP 407

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PTP-ER	NP_726092.1	PTP_DSP_cys	919..1362	CDD:475123	64/440 (15%)
F40G12.10	NP_506537.1	PTPc	144..397	CDD:214550	54/399 (14%)