DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PTP-ER and F57H12.5

DIOPT Version :9

Sequence 1:	NP_726092.1	Gene:	PTP-ER / 37461	FlyBaseID:	FBgn0016641	Length:	1377	Species:	Drosophila melanogaster
Sequence 2:	NP_501331.1	Gene:	F57H12.5 / 177592	WormBaseID:	WBGene00019020	Length:	543	Species:	Caenorhabditis elegans

Alignment Length:	182	Identity:	41/182 - (22%)
Similarity:	63/182 - (34%)	Gaps:	70/182 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly   882 ELKENEQKRIFRDLHKE---FWD------LPLNHQEKPMVFGSQTKNRYKTILP------NENSR 931
            |.|:.|:|.:.:|..:.   |.:      :...|.:|    .|:.|.:....:|      |:|:.
Worm   157 EEKKEEKKEVRKDCRENSVYFMERSDEKGVKKKHSKK----HSKQKTKMWLGMPSALNFCNKNND 217

  Fly   932 V-LLESESSELTSLLGEIKRTSSVTAS------------------------EDLPYINANYIK-- 969
            : .:..|...|.||:.. |.|.:..|:                        ||:.||||:.|.
Worm   218 IQKIREEFGFLDSLVCN-KTTEAFEANKVRNREGCPKIYDENRVQLNRPGHEDVNYINASVITLT 281

  Fly   970 --------GPDYV-------------SKCYVATQGPLPNTIF--EFWLMIYQ 998
                    .|.||             .|..||....:.|..|  :||.||||
Worm   282 DVCRRMACVPAYVHLVVLYFVIFQFEHKLIVAQLPQMENESFVEDFWYMIYQ 333

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PTP-ER	NP_726092.1	Y_phosphatase	916..1364	CDD:278528	32/139 (23%)
PTP-ER	NP_726092.1	PTPc	917..1364	CDD:238006	32/138 (23%)
F57H12.5	NP_501331.1	PTPc	220..500	CDD:214550	28/115 (24%)
F57H12.5	NP_501331.1	PTPc	255..498	CDD:304379	21/79 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0789
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900