Protein Alignment PTP-ER and C02B10.6

DIOPT Version :10

• Sequence 1: NP_726092.1
• Gene: PTP-ER / 37461
• FlyBaseID: FBgn0016641
• Length: 1377
• Species: Drosophila melanogaster
• Sequence 2: NP_500718.1
• Gene: C02B10.6 / 177279
• WormBaseID: WBGene00015331
• Length: 398
• Species: Caenorhabditis elegans
• Alignment Length: 531
• Identity: 110/531 - (20%)
• Similarity: 163/531 - (30%)
• Gaps: 246/531 - (46%)

  Fly   848 DVETPTDMVPPSSEDSELLASYQTVVSRMAQPIPELKENEQKRIFRDLHK----EFWDLPLNHQE 908
            |....|:|.|...:...::.  |.|:..:...:.:|:|.     ||.|.|    :...:..|..:
 Worm    69 DPTNKTNMTPAPPQTHPIVE--QWVLRALDVGVDKLREE-----FRGLAKYTRPDMTQVMFNANQ 126

  Fly   909 KPMVFGSQTKNRYKTILPNENSRVLLESESSELTSLLGEIKRTSSVTASEDLPYINANYIKGPDY 973
            .|.:  :.|||||:.:...:.|.|.|:..|                    ...||:|||:..|..
 Worm   127 SPDI--AITKNRYQDVPCQDQSAVKLDQPS--------------------PCNYIHANYVGCPMI 169

  Fly   974 VSKCYVATQGPLPNTIFEFWLMIYQNTQRYIRRCVDGGSSSSPHVDREQILQQYFQKIVMLTNFT 1038
            ..|.::..||||..||.|||.|:.||.                           .::||||....
 Worm   170 PEKRFICAQGPLDQTIDEFWWMVIQNK---------------------------VEQIVMLCKTV 207

  Fly  1039 EANRQKCAVYFPIELNEIFAVAAKCEVFQLSAA---ARDYFDRYLTPTFVPDTVVASSDAIDYEI 1100
            |..:.|||.|:|....|...:.:.|.|..:|.:   .||           |:
 Worm   208 EMGKLKCAQYWPAAQGEKLTLKSGCVVENVSGSKPMERD-----------PE------------- 248

  Fly  1101 SGRHIGVESVKVTLEGDLLEALPAQGSFFLIKNVGIVRRNGYSVRKLVLLYCIRVPQSASYHLQK 1165
                |.:..:.:|..|.                      ...|||                |||
 Worm   249 ----IQITMLNLTYSGG----------------------QTMSVR----------------HLQ- 270

  Fly  1166 IYCYHYWYPDWPDHHSPRDINTLLDTCLHVLNLGKCESEFDIYDDTRSERNAHLAAQRLEIYQQD 1230
                   :.:|||...|                 .|                       ::...:
 Worm   271 -------WTEWPDRGVP-----------------PC-----------------------KLTSLE 288

  Fly  1231 IFNAVQ----PLPVIHCSAGIGRTGCFTAILNAVRQLRQSLAYSLTGMLTKSLTSSSTEEYHNPT 1291
            :.:|::    |: |:||||||||||
 Worm   289 LLSAIRGSKVPI-VVHCSAGIGRTG---------------------------------------- 312

  Fly  1292 DSDSSFTCNTIRHISHILDHRDAEAVKTPPSFDRLPKMPDIFVDVLGIVCNLRLQRGGMVQNSEQ 1356
                     ||..|.:||: :.||....||       ||:       :|..||.||...:||..|
 Worm   313 ---------TIVAIEYILE-KIAENKPCPP-------MPE-------LVKALRDQRAFSIQNDVQ 353

  Fly  1357 YELIHRAICLY 1367
            |..|||.:..|
 Worm   354 YLFIHRVMLNY 364

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PTP-ER	NP_726092.1	PTP_DSP_cys	919..1362	CDD:475123	91/449 (20%)
C02B10.6	NP_500718.1	PTPc	101..363	CDD:214550	103/494 (21%)