Protein Alignment PTP-ER and T22C1.8

DIOPT Version :10

• Sequence 1: NP_726092.1
• Gene: PTP-ER / 37461
• FlyBaseID: FBgn0016641
• Length: 1377
• Species: Drosophila melanogaster
• Sequence 2: NP_492194.1
• Gene: T22C1.8 / 172571
• WormBaseID: WBGene00011918
• Length: 591
• Species: Caenorhabditis elegans
• Alignment Length: 496
• Identity: 102/496 - (20%)
• Similarity: 152/496 - (30%)
• Gaps: 202/496 - (40%)

  Fly   872 VVSRMAQPIPELKENEQKRIF----RDLHK--------EFWDLPLNHQEKPM---VF-GSQTKNR 920
            ::.....|:.::    ||::|    .|..|        ||......:..:||   :| .:.||||
 Worm    96 IIPLKGDPLSDV----QKKVFFKFASDAVKKNPPEYSVEFMTKVKPYPGQPMERKIFDANPTKNR 156

  Fly   921 YKTILPNENSRVLLESESSELTSLLGEIKRTSSVTASEDLPYINANYIKGPDYVSKCYVATQGPL 985
            ||.::.|:.:||:|..                    ..|..||:|||:.|   ::..::.|||..
 Worm   157 YKDVVCNDITRVILSD--------------------GGDGDYIHANYVNG---LNAPFILTQGAT 198

  Fly   986 PNTIFEFWLMIYQNTQRYIRRCVDGGSSSSPHVDREQILQQYFQKIVMLTNFTEANRQKCAVYFP 1050
            ..|:.:||.|:......|                           ||||....|..:.|||.|:|
 Worm   199 AATVIDFWRMVVHTKTAY---------------------------IVMLCEVMEDGKAKCAQYYP 236

  Fly  1051 IELNEIFAVAAKCEVFQLSAAARDYFDRYLTPTFVPDTVVASSDAIDYEISGRHIGVESVKVTLE 1115
            .:..|..                         ||                     |..::..:||
 Worm   237 EKAGEAM-------------------------TF---------------------GAWTILCSLE 255

  Fly  1116 GDLLEALPAQGSFFLIKNVGIVRRNGYSVRKLVLLYCIRVPQSASYHLQKIYCYHYWYPDWPDHH 1180
            .|              |:..|::|. .|||.:         .:...|:.|    |.....|||..
 Worm   256 DD--------------KDANIIKRT-LSVRNV---------DNGKEHILK----HLHTKSWPDRC 292

  Fly  1181 SPRDINTLLDTCLHVLNLGKCESEFDIYDDTRSERNAHLAAQRLEIYQQDIFNAVQPLPVIHCSA 1245
            .|.....|| ..|:::.                                   .|..|: .:||||
 Worm   293 VPNSTMALL-RMLYIVR-----------------------------------TASGPV-TVHCSA 320

  Fly  1246 GIGRTGCFTAI---------------LNAVRQLRQSLAYSL------TGMLTKSLTSSSTEEYHN 1289
            ||||||.|.||               |...|.||.|.|.|:      ..::...:.......|.:
 Worm   321 GIGRTGTFVAIEACLQILTDGKELDLLGTCRALRNSRAGSIQVDIQYMALVQILINYGKDNGYWD 385

  Fly  1290 PTDSDSSFTCNTIRHISHILDHRDAEAVKTPPSFDRLPKMP 1330
            .:|.|......|......|......:.|.|.||...|..:|
 Worm   386 DSDLDDRVELLTWNIQQFIQTRGKVDHVPTTPSTPALNIIP 426

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PTP-ER	NP_726092.1	PTP_DSP_cys	919..1362	CDD:475123	89/433 (21%)
T22C1.8	NP_492194.1	Y_phosphatase	151..376	CDD:459674	80/385 (21%)