Protein Alignment PTP-ER and F55F8.7

DIOPT Version :9

• Sequence 1: NP_726092.1
• Gene: PTP-ER / 37461
• FlyBaseID: FBgn0016641
• Length: 1377
• Species: Drosophila melanogaster
• Sequence 2: NP_491657.2
• Gene: F55F8.7 / 172228
• WormBaseID: WBGene00018895
• Length: 491
• Species: Caenorhabditis elegans
• Alignment Length: 687
• Identity: 130/687 - (18%)
• Similarity: 209/687 - (30%)
• Gaps: 317/687 - (46%)

  Fly   610 SNHSITLKTGHTTTSCGDLNSMQQLQQQQAMLSAEKYNR--LNMRTNSTGSGSGSGSNVPTPKRG 672
            ||.:..|.:|:...||                 |.|.|:  :|..|.:
 Worm    14 SNTAALLASGYALWSC-----------------ASKKNKKDINSETKT----------------- 44

  Fly   673 LLERRGSNQSLTLNMGSILGGAAGTEIQMTDIVQPKVTVCSCAAANQAPHQRKFFSTENLNSSKA 737
             |::|.....|..:..:     :.:|.:.|            |:||:.|.|:|..|.|.:...|.
 Worm    45 -LDKRPQTAELVKDEKN-----SNSEEKKT------------ASANEVPAQKKLNSKEEVKKEKK 91

  Fly   738 NSQKFFGQVCFGSASDL-----QPNPQQDSVREDQAIGATCTCAGTVRNIMTRPLSPQTTSEEFK 797
            .|:           .||     ..:.:.|..:.|:..|             ::.||.:...||.|
 Worm    92 KSE-----------DDLLDVKKTVSKEDDKKKVDKKDG-------------SKKLSKKKLKEEKK 132

  Fly   798 IYLASIQMLQSASNPLNQFDLIRLNYVFDHSYQTNRNIIEQPPVLGSNARDVETPTDMVPPSSED 862
                      ..|..:|:...|......|...       ||||..||:.|.:
 Worm   133 ----------EKSKKVNKEKKISKTESDDEDN-------EQPPEPGSDPRKI------------- 167

  Fly   863 SELLASYQTVVSRM-AQPIPELKENEQKRIFRDLHKEFWDLPLN-----HQEKPMVFGSQTKNRY 921
                  :....::| .|.|.:|.:::.|..          :|.|     ::..|.:      |||
 Worm   168 ------WAFKAAKMKCQAISKLHQDKIKGY----------MPPNCTYTAYEANPDL------NRY 210

  Fly   922 KTILPNENSRVLLESESSELTSLLGEIKRTSSVTASEDLPYINANYIKGPDYVSKCYVATQGPLP 986
            ..:...|.:||:|:                     :.|..||:|::::.|......|:.||||||
 Worm   211 ADVRCIEETRVVLK---------------------NHDRDYIHASWMRMPGKDQSTYITTQGPLP 254

  Fly   987 NTIFEFWLMIYQNTQRYIRRCVDGGSSSSPHVDREQILQQYFQKIVMLTNFTEANRQKCAVYFPI 1051
            .|:.:||.||||....|                           ::||....|...:|||:|:|.
 Worm   255 ETLSDFWHMIYQEKIAY---------------------------VLMLCTLFEGGVEKCALYYPE 292

  Fly  1052 ELNEIFAVAAKCEVFQLSAAARDYFDRY-LTPTFVPDTVVASSDAIDYEISGRHIGVESVKVTLE 1115
            :|.|:..                 |.:| :|.|...:..:|
 Worm   293 KLGEVVK-----------------FGKYEITLTECKEEAIA------------------------ 316

  Fly  1116 GDLLEALPAQGSFFLIKNVGIVRRNGYSVRKLVLLYCIRVPQSASYHLQKIYCYHYWYPDWPDHH 1180
            |.:|.:|..                            |....:.|   :.:|..|...|.|||..
 Worm   317 GTILNSLTV----------------------------INTEDATS---EPLYMNHVQVPWWPDQL 350

  Fly  1181 SPRDINTLLDTCLHVLNLGKCESEFDIYDDTRSERNAHLAAQRLEIYQQDIFNAVQP--LPV-IH 1242
            :|.|                                   |...:|:|:.  ...|.|  .|: :|
 Worm   351 APED-----------------------------------ARPMIELYKW--VKKVNPKEKPICVH 378

  Fly  1243 CSAGIGRTGCFTAI---------------LNAVRQLR 1264
            ||||:|||..|..|               |:.||::|
 Worm   379 CSAGVGRTATFVGIDYATIRIMENPNIEMLDIVREMR 415

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PTP-ER	NP_726092.1	Y_phosphatase	916..1364	CDD:278528	75/368 (20%)
		PTPc	917..1364	CDD:238006	75/367 (20%)
F55F8.7	NP_491657.2	PTPc	193..437	CDD:214550	78/386 (20%)
		PTPc	206..437	CDD:238006	75/373 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0789
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900