Protein Alignment PTP-ER and F47B3.6

DIOPT Version :10

• Sequence 1: NP_726092.1
• Gene: PTP-ER / 37461
• FlyBaseID: FBgn0016641
• Length: 1377
• Species: Drosophila melanogaster
• Sequence 2: NP_491275.3
• Gene: F47B3.6 / 171982
• WormBaseID: WBGene00018530
• Length: 363
• Species: Caenorhabditis elegans
• Alignment Length: 562
• Identity: 116/562 - (20%)
• Similarity: 170/562 - (30%)
• Gaps: 250/562 - (44%)

  Fly   832 NRN-IIEQ----PPVLGSNARDVE-------TPTDMVPPSSEDSELLASYQTVVSRMAQPIPELK 884
            |:| .:||    |.:..|:....:       ||| ..|||....:.:...:..|.|......:..
 Worm     7 NKNSTLEQKKKDPEITESSKNSSQPSQVPAATPT-AAPPSKAHQKAMIVVKPWVQRTLDMGVQAL 70

  Fly   885 ENEQKRIFRDLHKEFWDLPLNHQEKPMVFGSQT-KNRYKTILPNENSRVLLESESSELTSLLGEI 948
            .:|    ||.|.|  |.......|   .|.:.| ||||:.:...:..|::::...
 Worm    71 VDE----FRVLAK--WTPEGMTTE---AFSANTDKNRYQDVPCQDKGRIVVKFPG---------- 116

  Fly   949 KRTSSVTASEDLPYINANYIKGPDYVSKCYVATQGPLPNTIFEFWLMIYQNTQRYIRRCVDGGSS 1013
                  .||:   ||:|||: |.....|.::..||||.||...||.|
 Worm   117 ------LASD---YIHANYL-GTATNPKKFICAQGPLENTQHSFWAM------------------ 153

  Fly  1014 SSPHVDREQILQQYFQKIVMLTNFTEANRQKCAVYFPIELNE--IFAVAAKCEVFQLSAAARDYF 1076
                     .:|:..:.::||.|..|..:.||..|:|:|..:  :|..|
 Worm   154 ---------AIQEKVECVIMLCNCIETGKIKCHQYWPLEQGQKLVFGEA---------------- 193

  Fly  1077 DRYLTPTFVPDTV-VASSDAIDYEISGRHIGVESVKVTLEGDLLEALPAQGSFFLIKNVGIVRRN 1140
                     |:|: ||:..|.......:.|.|.::||..         .|||
 Worm   194 ---------PNTISVANLGAKKMAPDEQCINVTTLKVDW---------GQGS------------- 227

  Fly  1141 GYSVRKLVLLYCIRVPQSASYHLQKIYCYHYWYPDWPDHHSPRDINTLLDTCLHVLNLGKCESEF 1205
                         |..|    |||        :.:|||...|:       |.|..:||
 Worm   228 -------------RTIQ----HLQ--------WENWPDRGVPQ-------TNLTAINL------- 253

  Fly  1206 DIYDDTRSERNAHLAAQRLEIYQQDIFNAVQPLPVIHCSAGIGRTGCFTAILNAVRQLRQSLAYS 1270
              ...||..:|                    |: ::||||||||||...||           ||.
 Worm   254 --LSATRGNQN--------------------PI-LVHCSAGIGRTGTIVAI-----------AYV 284

  Fly  1271 LTGMLTKSLTSSSTEEYHNPTDSDSSFTCNTIRHISHILDHRDAEAVKTPPSFDRLPKMPDIFVD 1335
            ...|:......:..|
 Worm   285 QDKMMAGENCMAMNE-------------------------------------------------- 299

  Fly  1336 VLGIVCNLRLQRGGMVQNSEQYELIHRAICLYL----KRTLA 1373
               ::..||..|...:||..||..:||.:..|.    |.|.|
 Worm   300 ---LIKELRSHRPWSIQNEFQYLYLHRVLLSYFLERYKETYA 338

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PTP-ER	NP_726092.1	PTP_DSP_cys	919..1362	CDD:475123	86/445 (19%)
F47B3.6	NP_491275.3	Y_phosphatase	93..326	CDD:459674	90/452 (20%)