Protein Alignment PTP-ER and pph-7

DIOPT Version :10

• Sequence 1: NP_726092.1
• Gene: PTP-ER / 37461
• FlyBaseID: FBgn0016641
• Length: 1377
• Species: Drosophila melanogaster
• Sequence 2: NP_491071.1
• Gene: pph-7 / 171861
• WormBaseID: WBGene00022110
• Length: 557
• Species: Caenorhabditis elegans
• Alignment Length: 541
• Identity: 102/541 - (18%)
• Similarity: 154/541 - (28%)
• Gaps: 266/541 - (49%)

  Fly   842 LGSNARDVETPTDMVPPSSED-SELLASYQTVVSRMAQPIPELKENEQKRI-------------- 891
            |||..:|:|      |...|. :|::..:   .|.:....|:....|.|.:
 Worm   141 LGSEKKDLE------PKEKEQRAEMIKKW---ASAVMMSTPQQLTKEYKAVGNIVSDSECTAFLK 196

  Fly   892 FRDLHKEFWDLPLNHQEKPMVFGSQTKNRYKTILPNENSRVLLESESSELTSLLGEIKRTSSVTA 956
            |:||                       |||..|...:..|..|                     |
 Worm   197 FKDL-----------------------NRYPNIQCWDRGRFTL---------------------A 217

  Fly   957 SEDLPYINANYIK---GPDYVSKCYVATQGPLPNTIFEFWLMIYQNTQRYIRRCVDGGSSSSPHV 1018
            .::..||:||::|   .|:.    :|.||||:.||...||.|           .:..||:|
 Worm   218 GDENFYIHANFVKICTKPER----FVCTQGPMENTCTHFWQM-----------ALSLGSTS---- 263

  Fly  1019 DREQILQQYFQKIVMLTNFTEANRQKCAVYFP-----IELNEIFAVAAKCEVFQLSAAARDYFDR 1078
                        |:||..|.|...:|||.|..     :.|.:.......|...::...::|
 Worm   264 ------------IIMLCGFVEDGSEKCAKYISDIVGFVNLEDHRVYTEYCTEIEIGGKSKD---- 312

  Fly  1079 YLTPTFVPDTVVASSDAIDYEISGRHIGVESVKVTLEGDLLEALPAQGSFFLIKNVGIVRRNGYS 1143
                                :|:.|.:.|                            :|:..|
 Worm   313 --------------------KITHRVLKV----------------------------VVKATG-- 327

  Fly  1144 VRKLVLLYCIRVPQSASYHLQKIYCYHYWYPDWPDHHSPRDINTLLDTCLHVLNLGKCESEFDIY 1208
                                |:....||.:..||||..|..    .||.|.:|:..|.:.:
 Worm   328 --------------------QESKLNHYQWASWPDHGMPDS----CDTALRLLSAVKKDKK---- 364

  Fly  1209 DDTRSERNAHLAAQRLEIYQQDIFNAVQPLPVI-HCSAGIGRTGCFTAILNAVRQLRQSLAYSLT 1272
                                          ||| |||||:||||....|.:.:..||.
 Worm   365 ------------------------------PVIAHCSAGVGRTGTLALIESMIAALRH------- 392

  Fly  1273 GMLTKSLTSSSTEEYHNPTDSDSSFTCNTIRHISHILDHRD-AEAVKTPPSFDRLPKMPDIFVDV 1336
                        ....|..|             |.:|..:| |.:|:|.|.:            |
 Worm   393 ------------PRKQNVKD-------------SFVLLRKDRARSVQTFPQY------------V 420

  Fly  1337 LGIVCNLR-LQRGGMVQNSEQ 1356
            ..:.|.|. |...|:.:.:||
 Worm   421 YALRCVLEFLYSKGLYKRNEQ 441

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PTP-ER	NP_726092.1	PTP_DSP_cys	919..1362	CDD:475123	87/449 (19%)
pph-7	NP_491071.1	PTPc	177..428	CDD:214550	87/481 (18%)