Protein Alignment PTP-ER and Ptprg

DIOPT Version :9

• Sequence 1: NP_726092.1
• Gene: PTP-ER / 37461
• FlyBaseID: FBgn0016641
• Length: 1377
• Species: Drosophila melanogaster
• Sequence 2: NP_599183.2
• Gene: Ptprg / 171357
• RGDID: 620774
• Length: 1442
• Species: Rattus norvegicus
• Alignment Length: 1233
• Identity: 226/1233 - (18%)
• Similarity: 372/1233 - (30%)
• Gaps: 516/1233 - (41%)

  Fly   322 SAANESELSIVVHNITESHGSCDDMETGQSQPSTSVIHHHLHLQQPASAIHSTSLSRLDSHLSLA 386
            |..:.|.|..::|.:                  ..|:||..........:.....:.|.|:....
  Rat   207 SPRDNSALDPIIHGL------------------KGVVHHEKETFLDPFVLRDLLPASLGSYYRYT 253

  Fly   387 NQRRTPRRKSPGINTTDWLM--------YHRKQNPYQV----QPTHCSST--------TQSSLDS 431
            ....||    |.....:|::        ||:.:..|.:    |..|..|.        .|.:| :
  Rat   254 GSLTTP----PCSEIVEWIVFRRPVPISYHQLEAFYSIFTTEQQDHVKSVEYLRNNFRPQQAL-N 313

  Fly   432 DASLTPS---------LGDFELKSACSVDGGSKFGIGASLAPRSAHKHNQLLHSSSTNLK---TL 484
            |..::.|         |.||       :|  :..|..||....|...|.::...:.|.|:   :.
  Rat   314 DRVVSKSAVRDAWNHDLADF-------LD--NPLGTEASKVCSSPPIHMKVQPLNQTALQVSWSQ 369

  Fly   485 PECL-------TLVEFS-SSGGGPKESPF-KQKSMDLPMPTLQAKTTVSTSSMNLLQRRGSNHSL 540
            ||.:       .::.:| :.....||..| |....||       |.|:|..|.:.|        .
  Rat   370 PETIYHPPIMNYMISYSWTKNEDEKEKTFTKDSDKDL-------KATISHISPDSL--------Y 419

  Fly   541 TLNLHSSCGNLMNSGLSHSNYSLGSILNSKSSCNLDAGTASQIRADQLPQSHLLGSSQGSRQGLF 605
            ...:.:.|.|.|.|..|.:                           .|.|::.....||:|
  Rat   420 LFRVQAVCRNDMRSDFSQT---------------------------MLFQANTTRIFQGTR---- 453

  Fly   606 RRRGSNHSITLKTGHTTTSCGDLNSMQQLQQQQAMLSAE--KYNRLNMRTNSTGSGSGSGSNVPT 668
                     .:|||..|.|......|..:....:..::.  .::.::|.|....|.|||.:.|
  Rat   454 ---------IVKTGVPTASPASSADMAPISSGSSTWTSSGIPFSFVSMATGMGPSSSGSQATV-- 507

  Fly   669 PKRGLLERRGSNQSLTLNMGSILGGAAGTEIQMTDIVQPKVTVCSCAAANQ-------------- 719
                     .|..:.||..|...||...:....|  |.|.....:.||:.|
  Rat   508 ---------ASVVTSTLLAGLGFGGGGISSFPST--VWPTRLPTASAASKQAGRPVLATTEALAS 561

  Fly   720 -------APHQRKFFSTENLNSSKANSQKFFGQVCFGSASDLQPNPQQDSVREDQAIGATCTCAG 777
                   ||.:....:.|.....|:.|:         .....|...::||.::::: .||.|.|.
  Rat   562 PGPDGDSAPTKDGEGAEEGEKEEKSESE---------DGEREQEEEEKDSEKKEKS-EATHTAAE 616

  Fly   778 TVRNI-MTRPLSPQTTSEE----------------------------FKIYLASIQMLQSAS--- 810
            :.:.. ...|.||..|::|                            ..:...:.|:..:|:
  Rat   617 SDQTAPAPTPSSPHRTAQEGGHQTIPGHRQDHSAPVTDQPGHVDPGLDTLVDTATQVPPTATEEH 681

  Fly   811 --------------NPLNQFDLIRLNYVF---DHSYQTNRNIIEQP---------PVL------- 842
                          .|:::.|....:..|   :.:.:....:|.:|         |::
  Rat   682 YSGSDPKRPEMPSKKPISRGDRFSEDSKFITVNPAEKNTSGMISRPSPGRMEWIIPLIVVSALTF 746

  Fly   843 --------------GSN----------ARDVET-----------------------------PTD 854
                          |.|          :|:|.:                             |.:
  Rat   747 VCLVLLIAVLVYWRGCNKIKSKGFPRRSREVPSSGERGEKGSRKCFQTAHFYVEDSSSPRVVPNE 811

  Fly   855 MVP--PSSEDSELLASYQTVVSRMAQPIPELKENEQKRI---FRDLHKEFWDLPL--NHQEKPMV 912
            .:|  |..:|.|.:.     |.:..:.|.||..|.|...   |.::.:...|:.:  .|...|
  Rat   812 SIPIIPIPDDMEAIP-----VKQFGKHIGELYSNSQHGFSGDFEEVQRCTADMNITAEHSNHP-- 869

  Fly   913 FGSQTKNRYKTILPNENSRVLLESESSELTSLLGEIKRTSSVTASEDLPYINANYIKGPDYVSKC 977
             .::.||||..||..::|||       :|..|.|:..:.|.        ||||||:.|.: .:|.
  Rat   870 -DNKHKNRYINILAYDHSRV-------KLRPLPGKDSKHSD--------YINANYVDGYN-KAKA 917

  Fly   978 YVATQGPLPNTIFEFWLMIY-QNTQRYIRRCVDGGSSSSPHVDREQILQQYFQKIVMLTNFTEAN 1041
            |:||||||.:|..:||.||: |||                            ..|:|:||..|..
  Rat   918 YIATQGPLKSTFEDFWRMIWEQNT----------------------------GIIIMITNLVEKG 954

  Fly  1042 RQKCAVYFPIELNEIFAVAAKCEVFQLSAAARDYFDRYLTPTFVPDTVVASSDAIDYEISGRHIG 1106
            |:||..|:|.|..|.:.
  Rat   955 RRKCDQYWPTENTEEYG------------------------------------------------ 971

  Fly  1107 VESVKVTLEGDLLEALPAQGSFFLIKNVGIVRRNGYSVRKLVLLYCIRVPQSASYHLQKIYCYHY 1171
              ::.|||:...:.|...            |||  :|||...:....:.......:.:.:..||
  Rat   972 --NIIVTLKSTEVHACYT------------VRR--FSVRNTKVKKGQKGNPKGRQNERTVIQYH- 1019

  Fly  1172 WYPDWPDHHSPRDINTLLDTCLHVLNLGKCESEFDIYDDTRSERNAHLAAQRLEIYQQDIFNAVQ 1236
             |..|||...|       :..|.||...:..|...:.|                         :.
  Rat  1020 -YTQWPDMGVP-------EYALPVLTFVRRSSAARMPD-------------------------MG 1051

  Fly  1237 PLPVIHCSAGIGRTGCFTAILNAVRQLRQSLAYSLTGMLTKSLTSSSTEEYHNPTDSDSSFTCNT 1301
            |: ::|||||:||||.:..|.:.::|::                ..||
  Rat  1052 PV-LVHCSAGVGRTGTYIVIDSMLQQIK----------------DKST----------------- 1082

  Fly  1302 IRHISHILDHRDAEAVKTPPSFDRLPKMPDIFVDVLGIVCNLRLQRGGMVQNSEQYELIHRAI 1364
                                            |:|||.:.::|.||..:||..|||..||.|:
  Rat  1083 --------------------------------VNVLGFLKHIRTQRNYLVQTEEQYIFIHDAL 1113

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PTP-ER	NP_726092.1	Y_phosphatase	916..1364	CDD:278528	98/448 (22%)
		PTPc	917..1364	CDD:238006	98/447 (22%)
Ptprg	NP_599183.2	alpha_CARP_receptor_like	67..319	CDD:239396	22/134 (16%)
		FN3	348..438	CDD:238020	23/104 (22%)
		R-PTPc-G-1	845..1118	CDD:350505	103/480 (21%)
		R-PTP-G-2	1202..1406	CDD:350508

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0789
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900