Protein Alignment PTP-ER and mop

DIOPT Version :10

• Sequence 1: NP_726092.1
• Gene: PTP-ER / 37461
• FlyBaseID: FBgn0016641
• Length: 1377
• Species: Drosophila melanogaster
• Sequence 2: XP_061514557.1
• Gene: mop / 1271173
• VectorBaseID: AGAMI1_014214
• Length: 1778
• Species: Anopheles gambiae
• Alignment Length: 1053
• Identity: 200/1053 - (18%)
• Similarity: 336/1053 - (31%)
• Gaps: 346/1053 - (32%)

  Fly    37 AGEDAESNKSTPYFTPLEYLQTSFEFPSPTVEV-GGGVPGFPE----------HEDQEEEVFTPR 90
            ||.|.:.....|...|   .....|..:|.|.: |||..|:.:          |:.|:::....:
Mosquito   776 AGVDKKPATHLPSVRP---APVGSESNAPVVGIAGGGTGGYYQDSYTNYHQQYHQQQQQQQQQQQ 837

  Fly    91 QFTITSPHPAAHVHHPSSSQSPTLGRKFKRLSQYDRRSCSPHINTSSGEERVSGRGIDKENTMPK 155
            |          .:.:..:|.....|..:: .|||      ..:|.|..:...:|..:       .
Mosquito   838 Q----------QMQYGGNSNMSVAGTGYE-YSQY------ATLNQSQPQPSATGSTV-------A 878

  Fly   156 GGSVDQDLEN----SLYLSKSEHNSPTILFKDESSTTPGLE------------ASRLSYSPKLLS 204
            .|.|:...:|    :.|.:.::...|      :||.|.|.:            |.:.|.:|...|
Mosquito   879 TGYVNPMYQNQTSTNYYYNNNQAQVP------QSSNTTGYDYGQYGQQQMPPPAQQPSPAPSASS 937

  Fly   205 ----------SINNLNVSGSPLNIINSAGYKNGNFFRFPEIDHVVQDAPMDTVCLEEATRRDRSP 259
                      |...||...|.:|:                     |....|.....:......:|
Mosquito   938 ASSDVAQQQASWGQLNQQFSAMNL---------------------QQPTADGSYANQTAGTSSNP 981

  Fly   260 ALAEPP---------EQQQQKSEGRKNRKNKNNLTIRITDVPIKNSSQPSPLPKPKTPTIKSTKE 315
            ..::..         :||||:.:.::                ....|||:..|.| .||  |:.|
Mosquito   982 GYSQVAAYQSSVGVNQQQQQQQQQQQ----------------YPTVSQPNAYPTP-YPT--SSNE 1027

  Fly   316 KARSLDSAANESELSIVVHNITESHGSCDDMETGQSQPSTSVIHHHLHLQQPASAIHSTSLSRLD 380
            ...|:.|:.:.:        :|.::|:     .||:.|....      .||||
Mosquito  1028 SMTSVSSSQDAA--------VTAAYGN-----YGQTVPQQQA------YQQPA------------ 1061

  Fly   381 SHLSLANQRRTPRRK-SPGINTTDWLMYHRKQNPYQVQPTHCSSTTQSSLDSDA--SLTPSLGDF 442
                       |::. ..|.:||.:.    :|.|||.:.|       :|..|..  |..|..|.:
Mosquito  1062 -----------PQQTYGAGSSTTPYY----QQAPYQTEQT-------ASYGSHPGYSYNPQTGAY 1104

  Fly   443 ELKSACSVDGGSKFGIGASLAPRSAHKHNQLLHSSSTNLKTLPECLTLVEFSSSG--------GG 499
            :..|....|  |......|.|  :.:..|..|.|||          ....:|:||        ..
Mosquito  1105 DYTSGFQCD--SNNATAGSYA--NQYVSNPQLGSSS----------MATTYSASGQTAAPASVDS 1155

  Fly   500 PKESPFKQKSMDLPMPTL--QAKTTVSTSSMNLLQRRGSNHSLTLNLHSSCGNLMNSGLSHSNYS 562
            ....|::..:...|.|:.  |.:...:|||.               .:::.|...::|..|...:
Mosquito  1156 SASQPYQLSTGGTPAPSAYPQGQPANATSSY---------------YNTTSGAATSAGYYHQTST 1205

  Fly   563 LGSI-LNSKSSCNLDAGTASQIRADQLPQSHLLGSSQGSRQGLFRRRGSNHSITLKTGHTTTSCG 626
            ..:: .|...:...|..|..| ::...|.:|...:...:....:....:::..:..:.:|||:..
Mosquito  1206 YSTVQSNQYLASQPDPVTVVQ-QSPLPPAAHSTPNDPTANVAHYSHHTNSYVDSTGSQNTTTTTA 1269

  Fly   627 DLNSMQQLQQQQAMLSAEKYNRLNMRTNSTGSG-SGSGSNVPTPKRGLLERRGSNQSLTLNMGSI 690
            . :|.....|||:::|.:.....|:   ...|| ..|.:.||.....:|:.:.:       .|||
Mosquito  1270 S-SSSSSTTQQQSVVSPQTTQSKNI---DLLSGIDFSPALVPPIAAPILQPQPT-------AGSI 1323

  Fly   691 LGGAA--GTEIQMTDIVQP-KVTVCSCAAANQAPHQRKFFSTENLNSSKANSQKFFGQVCFGSAS 752
            :|..|  |:|...:.|:.| |.||                 .|.|...||
Mosquito  1324 VGSTAVDGSEAAASVILTPTKATV-----------------VEKLVVEKA--------------- 1356

  Fly   753 DLQPNPQQDSVREDQAIGATCTCAGTVRNIMTRPLSPQTTSEEFKIYLASIQMLQSASNPLNQFD 817
             :.|:|.|   ....|:...|               |....|.    ..|:..|...|:..:.||
Mosquito  1357 -VVPDPTQ---TVPTAVPTAC---------------PSVIGER----KPSLDNLSLCSDLSSSFD 1398

  Fly   818 LIRLNYVFDHSYQTNRNIIEQPPVLGSNAR---DVETPTDMV------PPSSEDSELLASYQTVV 873
            .                  |...|.|:.|.   ....|.|.|      |...||...|..:...|
Mosquito  1399 W------------------ESASVCGATASVSGAAANPADNVFLRPTKPDPFEDGATLKWFHKEV 1445

  Fly   874 SRMAQPIPE--LKENEQKRIFRDLHKEFWDLPLNHQEKPMVFGSQ---TKNRYKTILPNENSRVL 933
            .|:.:.:..  :|............||..||.:..:.|..|..::   .|||....:|.:::||.
Mosquito  1446 ERLEKFVETSGVKTLNGTTPLDSKWKELQDLLVKEEAKRQVSVARLFPEKNRSIDCVPYDHARVQ 1510

  Fly   934 LESESSELTSLLGEIKRTSSVTASEDLPYINANYIKGP-----DYVSKC--YVATQGPLPNTIFE 991
            |.:::..                     ||||.|:|..     |....|  ::..|.|||||:.:
Mosquito  1511 LSTDTDN---------------------YINAVYVKFQKDSKLDLGFGCPHFILAQAPLPNTVND 1554

  Fly   992 FWLMIYQNTQRYI 1004
            ||.||:......|
Mosquito  1555 FWNMIWSQKSNVI 1567

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PTP-ER	NP_726092.1	PTP_DSP_cys	919..1362	CDD:475123	25/93 (27%)
mop	XP_061514557.1	None