Protein Alignment PTP-ER and Ptpn23

DIOPT Version :9

• Sequence 1: NP_726092.1
• Gene: PTP-ER / 37461
• FlyBaseID: FBgn0016641
• Length: 1377
• Species: Drosophila melanogaster
• Sequence 2: NP_476552.2
• Gene: Ptpn23 / 117552
• RGDID: 619892
• Length: 1666
• Species: Rattus norvegicus
• Alignment Length: 458
• Identity: 89/458 - (19%)
• Similarity: 136/458 - (29%)
• Gaps: 223/458 - (48%)

  Fly   918 KNRYKTILPNENSRVLLESESSELTSLLGEIKRTSSVTASEDLPYINANYIKGPDYVSKCYVATQ 982
            |||::.::|.:::||:|.|...:                     ||||:.::|........||||
  Rat  1250 KNRHQDVMPYDSNRVVLRSGKDD---------------------YINASCVEGLSPYCPPLVATQ 1293

  Fly   983 GPLPNTIFEFWLMIYQNTQRYIRRCVDGGSSSSPHVDREQILQQYFQKIVMLTNFTEANRQKCAV 1047
            .|||.|..:||||::                           :|....||||.:..|..:||.|.
  Rat  1294 APLPGTAADFWLMVH---------------------------EQKVSVIVMLVSEAEMEKQKVAR 1331

  Fly  1048 YFPIELNEIFAVAAKCEVFQLSAAARDYFDRYLTPTFVPDTVVASSDAIDYEISGRHIGVESVKV 1112
            |||||..:.....|      ||.|        |:.....||.|....::.:.       .:|:|
  Rat  1332 YFPIERGQPMVHGA------LSVA--------LSSVRTTDTHVERVLSLQFR-------DQSLK- 1374

  Fly  1113 TLEGDLLEALPAQGSFFLIKNVGIVRRNGYSVRKLVLLYCIRVPQSASYHLQKIYCYHYWYPDWP 1177
                                            |.||                     |..:|.||
  Rat  1375 --------------------------------RSLV---------------------HLHFPTWP 1386

  Fly  1178 DHHSPRDINTLLDTCLHVLNLGKCESEFDIYDDTRSERNAHLAAQRLEIYQQDIFNAVQPLP--- 1239
            :...|.....||...                    .|.:||...||             ||.
  Rat  1387 ELGLPDSPGNLLRFI--------------------QEVHAHYLHQR-------------PLHTPI 1418

  Fly  1240 VIHCSAGIGRTGCFTAILNAVRQLRQSLAYSLTGMLTKSLTSSSTEEYHNPTDSDSSFTCNTIRH 1304
            |:|||:|:||||.|..:..||:::...
  Rat  1419 VVHCSSGVGRTGAFALLYAAVQEVEAG-------------------------------------- 1445

  Fly  1305 ISHILDHRDAEAVKTPPSFDRLPKMPDIFVDVLGIVCNLRLQRGGMVQNSEQYELIHRAICLYLK 1369
                               ..:|::|.       :|..:|.||..|:|.....:..|.|:..:::
  Rat  1446 -------------------SGIPELPQ-------LVRRMRQQRKHMLQEKLHLKFCHEALVRHVE 1484

  Fly  1370 RTL 1372
            :.|
  Rat  1485 QVL 1487

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PTP-ER	NP_726092.1	Y_phosphatase	916..1364	CDD:278528	87/448 (19%)
		PTPc	917..1364	CDD:238006	87/448 (19%)
Ptpn23	NP_476552.2	BRO1_HD-PTP_like	2..357	CDD:185762
		V_HD-PTP_like	362..702	CDD:185747
		ALIX_LYPXL_bnd	417..703	CDD:290660
		Y_phosphatase	1250..1480	CDD:278528	88/449 (20%)
		PTPc	1250..1479	CDD:238006	87/448 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0789
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900