DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment ASPG and ASP3-4

DIOPT Version :9

Sequence 1:XP_016876754.1 Gene:ASPG / 374569 HGNCID:20123 Length:670 Species:Homo sapiens
Sequence 2:NP_013261.1 Gene:ASP3-4 / 850857 SGDID:S000004150 Length:362 Species:Saccharomyces cerevisiae


Alignment Length:320 Identity:77/320 - (24%)
Similarity:116/320 - (36%) Gaps:87/320 - (27%)


- Green bases have known domain annotations that are detailed below.


Human    58 PSSARGEQSGSGHLEQEEVQSGSLLFRLLLFLSRSPASRNQRILYTVLECQPLFDSSDMTIAEWV 122
            ||.|  |::...:|:...|.|.||.:..|:                     ||:......:|.  
Yeast    71 PSLA--EKANLDYLQVSNVGSNSLNYTHLI---------------------PLYHGISEALAS-- 110

Human   123 CLAQTIKRHYEQYHGFVVIHGTDTMAFAASMLSFMLENLQKTVILTGAQVPIHALWSDGRENLLG 187
                      :.|.|.||.||||||...|..|...: |.:|.|.:.||..|..|..:||..||..
Yeast   111 ----------DDYAGAVVTHGTDTMEETAFFLDLTI-NSEKPVCIAGAMRPATATSADGPMNLYQ 164

Human   188 ALLMAGQYVIPEVCLFFQNQLFRGNRATKVDARRFAAFCSP--NLLPLATVGADITINRELVRKV 250
            |:.:|..          :..|.||...|..| |..:.|.:.  |...|.|..||          .
Yeast   165 AVSIAAS----------EKSLGRGTMITLND-RIASGFWTTKMNANSLDTFRAD----------E 208

Human   251 DGKAGLVVHSSME-------------------------QDVGLLRLYPGI-PAALVRAFLQPPLK 289
            .|..|...:..:|                         .:|.:|..|.|: |..:|:|......|
Yeast   209 QGYLGYFSNDDVEFYYPPVKPNGWQFFDISNLTDPSEIPEVIILYSYQGLNPELIVKAVKDLGAK 273

Human   290 GVVMETFGSGNGPTKPDLLQELRVATERGLVIVNCTHCLQGAVTTDYAAGMAMAGAGVIS 349
            |:|:...|:|:......::.| ::..|.|:.||:......|.|..|.|...|: |:|.::
Yeast   274 GIVLAGSGAGSWTATGSIVNE-QLYEEYGIPIVHSRRTADGTVPPDDAPEYAI-GSGYLN 331

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ASPGXP_016876754.1 None
ASP3-4NP_013261.1 asnASE_II 9..359 CDD:273115 77/320 (24%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C159049102
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0252
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 1 0.900 - - OOG6_100658
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R2038
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
54.670

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