DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment twz and kctd7

DIOPT Version :9

Sequence 1:	NP_001246449.1	Gene:	twz / 37456	FlyBaseID:	FBgn0034636	Length:	367	Species:	Drosophila melanogaster
Sequence 2:	NP_001038798.2	Gene:	kctd7 / 735248	ZFINID:	ZDB-GENE-060804-2	Length:	339	Species:	Danio rerio

Alignment Length:	204	Identity:	57/204 - (27%)
Similarity:	91/204 - (44%)	Gaps:	37/204 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    63 SPTVSPTISNSSSPTPTPPASSSVTPLGLPGAV-----------AAAAAAVGGASSAGASSYLHG 116
            :|...|...:.|:..|...|:|.|......|..           ||:.:...|.:.:||......
Zfish     9 TPNGEPPPLSFSAAAPLQMATSRVRRFAQEGRTVPQPRVMVVFSAASDSEKPGDAMSGADKGEEE 73

  Fly   117 NHKPITGIP-----------CVAAASRYTAPVHIDVGGTIYTSSLETLTKYPESKLAKLFNGQIP 170
            ..||  .||           .:.|...:...:.::||||.:|:.|.||.:|.::.||.:|:|:..
Zfish    74 YRKP--AIPVANLNLAKSLRTLDAPEEFPEVIPLNVGGTYFTTRLSTLRRYEDTMLAAMFSGRHH 136

  Fly   171 IVLDSLKQHYFIDRDGGMFRHILNFMRNSRLLIAEDFPD---LELLLEEARYYEVEPMIKQLES- 231
            |..|: :..|||||||..|..||||:|...|      |.   :..:..||:||.:.|:::.||.
Zfish   137 IPRDA-EGRYFIDRDGTYFGDILNFLREGEL------PQRDRVRAVHREAQYYAIGPLLENLEDT 194

  Fly   232 --MRKDRVR 238
              :..::||
Zfish   195 QPLTGEKVR 203

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
twz	NP_001246449.1	BTB_POZ_KCTD1-like	137..230	CDD:349670	35/95 (37%)
kctd7	NP_001038798.2	BTB	105..193	CDD:197585	36/94 (38%)
kctd7	NP_001038798.2	BTB	105..188	CDD:295341	35/89 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170591937
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2723
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.740