Protein Alignment twz and Kctd21

DIOPT Version :9

• Sequence 1: NP_001246449.1
• Gene: twz / 37456
• FlyBaseID: FBgn0034636
• Length: 367
• Species: Drosophila melanogaster
• Sequence 2: NP_001034128.2
• Gene: Kctd21 / 622320
• MGIID: 3643121
• Length: 260
• Species: Mus musculus
• Alignment Length: 262
• Identity: 75/262 - (28%)
• Similarity: 121/262 - (46%)
• Gaps: 71/262 - (27%)

  Fly   136 PVHIDVGGTIYTSSLETLTKYPESKLAKLFNGQIPIVLDSLKQHYFIDRDGGMFRHILNFMRNSR 200
            |:.::|||.:||:||.|||.:|:|.|..:|:|::|...|| :.:.||||||.:||:||||:|.|.
Mouse     4 PITLNVGGKLYTTSLATLTSFPDSMLGAMFSGKMPTKRDS-QGNCFIDRDGKVFRYILNFLRTSH 67

  Fly   201 LLIAEDFPDLELLLEEARYYEVEPMIKQLESMR----------------KDRVRNGNYLVAPPTP 249
            |.:.|||.::.||..||.:|:|:|:|:.|:...                |.||:..::.|
Mouse    68 LDLPEDFQEMGLLRREADFYQVQPLIEALQEKEVELSKAEKNAMLNITLKQRVQTVHFTV----- 127

  Fly   250 PARHIKTSPRTSASPECNYEVVALHISPD-------LGERIMLSAERAL--------------LD 293
                 :.:|:..:....:.||...:|...       ||.::...:...|              ||
Mouse   128 -----REAPQIYSLSSSSMEVFNANIFSTSCLFLKLLGSKLFYCSNGNLSSITSHLQDPNHLTLD 187

  Fly   294 -----ELFPEASQATQSSRSGVSWNQGDWGQIIRFPLNGYCKLNSVQ-----VLTRLLNAGFTIE 348
                 |..||.....|:.:           ::...|.|.  ::||.|     ||...|:.||.|:
Mouse   188 WVANVEGLPEEEYTKQNLK-----------RLWVVPANK--QINSFQVFVEEVLKIALSDGFCID 239

  Fly   349 AS 350
            :|
Mouse   240 SS 241

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
twz	NP_001246449.1	BTB_POZ_KCTD1-like	137..230	CDD:349670	44/92 (48%)
Kctd21	NP_001034128.2	BTB_POZ_KCTD21	3..100	CDD:349703	46/96 (48%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167846736
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2723
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740