Protein Alignment twz and kctd15a

DIOPT Version :9

• Sequence 1: NP_001246449.1
• Gene: twz / 37456
• FlyBaseID: FBgn0034636
• Length: 367
• Species: Drosophila melanogaster
• Sequence 2: XP_005163108.1
• Gene: kctd15a / 449991
• ZFINID: ZDB-GENE-041010-105
• Length: 265
• Species: Danio rerio
• Alignment Length: 269
• Identity: 132/269 - (49%)
• Similarity: 177/269 - (65%)
• Gaps: 35/269 - (13%)

  Fly   105 ASSAGAS-SYLHGNHKPIT-----GIPCVAAASRYTAPVHIDVGGTIYTSSLETLTKYPESKLAK 163
            :|..|.| |.|.....|::     |||..|..::..|||||||||.:|||||.||||||:|::::
Zfish     2 SSKEGRSMSRLSLTRSPVSPLAAQGIPLPAQLTKSNAPVHIDVGGHMYTSSLATLTKYPDSRISR 66

  Fly   164 LFNGQIPIVLDSLKQHYFIDRDGGMFRHILNFMRNSRLLIAEDFPDLELLLEEARYYEVEPMIKQ 228
            ||||..|||||||||||||||||.:||:||:::|.|:||:.|||.:.:||.||||||::.||:|:
Zfish    67 LFNGTEPIVLDSLKQHYFIDRDGEIFRYILSYLRTSKLLLPEDFKEFQLLYEEARYYQLTPMVKE 131

  Fly   229 LESMRKDRVRNGNYLVAPPTPPARHIKTSPRTSASPECNYEVVALHISPDLGERIMLSAERALLD 293
            ||..:::|                    ..|.||.| |  |.:.:.::|||||||.:|.:::|::
Zfish   132 LERWKQER--------------------EQRRSAQP-C--ECLVVRVTPDLGERIAVSGDKSLIE 173

  Fly   294 ELFPEASQATQSSRSGVSWNQGDWGQIIRFPLNGYCKLNSVQVLTRLLNAGFTIEASVGG----Q 354
            |:|||......:| ....||| |...:|||||||||:|||||||.||...||::.||.||    .
Zfish   174 EIFPETGDVMCNS-VNAGWNQ-DPTHVIRFPLNGYCRLNSVQVLERLFQKGFSMVASCGGGVDSS 236

  Fly   355 QFSEYLLAR 363
            |||||:|:|
Zfish   237 QFSEYILSR 245

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
twz	NP_001246449.1	BTB_POZ_KCTD1-like	137..230	CDD:349670	62/92 (67%)
kctd15a	XP_005163108.1	BTB	40..135	CDD:197585	64/94 (68%)
		BTB	40..127	CDD:295341	59/86 (69%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170591936
Domainoid	1	1.000	136	1.000	Domainoid score	I4873
eggNOG	1	0.900	-	-		E1_KOG2723
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	235	1.000	Inparanoid score	I3365
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D412532at33208
OrthoFinder	1	1.000	-	-		FOG0002897
OrthoInspector	1	1.000	-	-		otm24279
orthoMCL	1	0.900	-	-		OOG6_108738
Panther	1	1.100	-	-	O	PTHR14499
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5816
SonicParanoid	1	1.000	-	-		X1912
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	14	13.790