Protein Alignment twz and KCNRG

DIOPT Version :9

• Sequence 1: NP_001246449.1
• Gene: twz / 37456
• FlyBaseID: FBgn0034636
• Length: 367
• Species: Drosophila melanogaster
• Sequence 2: NP_775876.1
• Gene: KCNRG / 283518
• HGNCID: 18893
• Length: 272
• Species: Homo sapiens
• Alignment Length: 235
• Identity: 60/235 - (25%)
• Similarity: 88/235 - (37%)
• Gaps: 73/235 - (31%)

  Fly   137 VHIDVGGTIYTSSLETLTKYPESKLAKLFNGQIPIVLDSLKQHY-------FIDRDGGMFRHILN 194
            |.::|||.|:|:...|:.::|.|:||::        ||...|.:       |:||||.:|..||:
Human     7 VTLNVGGKIFTTRFSTIKQFPASRLARM--------LDGRDQEFKMVGGQIFVDRDGDLFSFILD 63

  Fly   195 FMRNSRLLIAEDFPDLELLLEEARYYEVEPMIKQLE----------------------------- 230
            |:|..:||:..:|.|...|..||.:||:..::..|.
Human    64 FLRTHQLLLPTEFSDYLRLQREALFYELRSLVDLLNPYLLQPRPALVEVHFLSRNTQAFFRVFGS 128

  Fly   231 -----SMRKDRVR-----------NGNY-------LVAPPTPPARHIKTSPRTSASPECNYEVVA 272
                 .|...|:.           |||:       |..||..|:.|.......|.|...|...|.
Human   129 CSKTIEMLTGRITVFTEQPSAPTWNGNFFPPQMTLLPLPPQRPSYHDLVFQCGSDSTTDNQTGVR 193

  Fly   273 -LHISPD-----LGERIMLSAERALLDELFPEASQATQSS 306
             :.|.||     .|..::......||.|.|...|..|.||
Human   194 YVSIKPDNRKLANGTNVLGLLIDTLLKEGFHLVSTRTVSS 233

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
twz	NP_001246449.1	BTB_POZ_KCTD1-like	137..230	CDD:349670	33/99 (33%)
KCNRG	NP_775876.1	BTB	7..94	CDD:321966	33/94 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165156334
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2723
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.740