DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment twz and Tnfaip1

DIOPT Version :9

Sequence 1:	NP_001246449.1	Gene:	twz / 37456	FlyBaseID:	FBgn0034636	Length:	367	Species:	Drosophila melanogaster
Sequence 2:	NP_001152864.1	Gene:	Tnfaip1 / 21927	MGIID:	104961	Length:	316	Species:	Mus musculus

Alignment Length:	180	Identity:	40/180 - (22%)
Similarity:	91/180 - (50%)	Gaps:	33/180 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   119 KP-ITGIPCVAAASRYTAPVHIDVGGTIYTSSLETLTKYPESKLAKLFNGQIPIVLDSLKQHY-F 181
            || |:|.......::|   |.::|||::|.:::..||:: ::.|..:|:|::.::.|  |:.: .
Mouse    14 KPKISGFKGGGLGNKY---VQLNVGGSLYYTTVRALTRH-DTMLKAMFSGRMEVLTD--KEGWIL 72

  Fly   182 IDRDGGMFRHILNFMRNSRLLIAEDFPDLELLLEEARYYEVEPMIKQLESMRKDRVRNGNYLVAP 246
            |||.|..|..|||::|:..:.:.:...:::.|:.||:||.::.::...::..:|:
Mouse    73 IDRCGKHFGTILNYLRDDTITLPQSRQEIQELMAEAKYYLIQGLVSTCQTALQDK---------- 127

  Fly   247 PTPPARHIKTSPRTSASPECNYEVVALHISPDLGERIMLSAERALLDELF 296
                        :.|..|.||..::......|   |::.|:.:.::..|:
Mouse   128 ------------KDSYQPVCNIPIITSLREED---RLIESSTKPVVKLLY 162

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
twz	NP_001246449.1	BTB_POZ_KCTD1-like	137..230	CDD:349670	26/93 (28%)
Tnfaip1	NP_001152864.1	BTB	29..127	CDD:197585	27/103 (26%)
		BTB_2	30..120	CDD:280393	26/92 (28%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	268..288
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910