Protein Alignment twz and Kctd12b

DIOPT Version :9

• Sequence 1: NP_001246449.1
• Gene: twz / 37456
• FlyBaseID: FBgn0034636
• Length: 367
• Species: Drosophila melanogaster
• Sequence 2: NP_780638.1
• Gene: Kctd12b / 207474
• MGIID: 2444667
• Length: 292
• Species: Mus musculus
• Alignment Length: 284
• Identity: 63/284 - (22%)
• Similarity: 119/284 - (41%)
• Gaps: 72/284 - (25%)

  Fly   137 VHIDVGGTIYTSSLETLTKYPESKLAKLFNGQIP--IVLDSLKQHYFIDRDGGMFRHILNFMRNS 199
            :.::|||.:|.:...||...|.|:|.::|:.:.|  ::.|: |..:||||||.:||::|::||:.
Mouse    23 IELNVGGQVYITRYPTLISIPGSRLWEMFSVKNPCSLIQDN-KGRFFIDRDGFLFRYVLDYMRDM 86

  Fly   200 RLLIAEDFPDLELLLEEARYYE-------VEPMIKQLESMRKDRV-------------------R 238
            ::::.:.||:...|..||.|::       :.|.:.:|.|:..|..                   .
Mouse    87 QVVLPDHFPECGRLHREAEYFKLPELAKMLAPKMNKLNSIGNDSCPIDLEELSPSIDTTFNFSST 151

  Fly   239 NGNYLVAPPTPPARHIKTSPRTSASPECNYEVVALHISPDLGE------------RIMLSAERAL 291
            |..::..|..|..  ::.:| .|...:..:..:....|..||.            |||:..:.:|
Mouse   152 NSIHISGPDNPMV--LRAAP-GSELKKAGFITIGYRGSYTLGRDSQADAKFRRVARIMVCGKISL 213

  Fly   292 LDELFPEA-SQATQSSRSGVSWNQGDWGQIIRFPLNGYCKLNSV-QVLTRLLNAGFTIEA--SVG 352
            ..|:|.:. :::....|...           |:....|.|...: |...:|.:|||.:.|  |.|
Mouse   214 AKEVFGDTLNESRDPDRPPE-----------RYTSRYYLKFTFLEQAFDKLADAGFHMVACNSTG 267

  Fly   353 -------------GQQFSEYLLAR 363
                         ...::||:..|
Mouse   268 TCTVTHDQTDDRIWTSYTEYVFYR 291

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
twz	NP_001246449.1	BTB_POZ_KCTD1-like	137..230	CDD:349670	31/101 (31%)
Kctd12b	NP_780638.1	BTB_POZ_KCTD8-like	19..118	CDD:349676	30/95 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167846737
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2723
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.740