Protein Alignment twz and ZC239.15

DIOPT Version :10

• Sequence 1: NP_001246449.1
• Gene: twz / 37456
• FlyBaseID: FBgn0034636
• Length: 367
• Species: Drosophila melanogaster
• Sequence 2: NP_494481.2
• Gene: ZC239.15 / 191125
• WormBaseID: WBGene00022573
• Length: 232
• Species: Caenorhabditis elegans
• Alignment Length: 260
• Identity: 72/260 - (27%)
• Similarity: 112/260 - (43%)
• Gaps: 66/260 - (25%)

  Fly   137 VHIDVGGTIYTSSLETLTKYPESKLAKLFNGQIPIVLDS---LK----QHYFIDRDGGMFRHILN 194
            |.:||||||:.:|..||||         |||....:|:|   ||    ...||||....|..|||
 Worm     5 VKLDVGGTIFKTSRSTLTK---------FNGFFKTMLESDIGLKIDESGSIFIDRSPKNFDLILN 60

  Fly   195 FMRNSRLLIAEDFPDLEL----LLEEARYYEVEPMIKQLESMRKDRVRNGNYLVAPPTPPARHIK 255
            |||:..:::    |:.||    ||.||::|.::.:|:...|..:        ||..|....|.|:
 Worm    61 FMRDGDVVL----PNCELKLKELLVEAQFYLLDGLIELCNSKIE--------LVEAPKIKLRFIE 113

  Fly   256 TSPRTSASPECNYEVVALHISPDL-GERIMLSAERAL----------------LDELFPEASQAT 303
                   |.|...:::|:...|.| .|..|:..:.::                .|..|...|:..
 Worm   114 -------SDEQFLQILAVQQKPMLIIEFCMVGNDMSIPYNFNLYEFMEKYSHQFDIYFQRLSEDE 171

  Fly   304 QSS--RSGVSWNQGDWGQIIRFPLNGYCKLNSVQVLTRLLNAGF--TIEASVGGQQFSEYLLARR 364
            .|.  ::.:.|...:.|...:||.|  .::|....:.|  :|.|  .:|..:|  :|.|||..:|
 Worm   172 PSRKWKARIKWKPTENGYYSQFPHN--LRINRGGRIIR--DATFLERLEKMIG--EFDEYLKKQR 230

  Fly   365  364
             Worm   231  230

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
twz	NP_001246449.1	BTB_POZ_KCTD1-like	137..230	CDD:349670	39/103 (38%)
ZC239.15	NP_494481.2	BTB_2	5..95	CDD:426665	39/102 (38%)