DRSC/TRiP Functional Genomics Resources

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Protein Alignment twz and F22E5.8

DIOPT Version :9

Sequence 1:NP_001246449.1 Gene:twz / 37456 FlyBaseID:FBgn0034636 Length:367 Species:Drosophila melanogaster
Sequence 2:NP_001364741.1 Gene:F22E5.8 / 173610 WormBaseID:WBGene00017707 Length:232 Species:Caenorhabditis elegans


Alignment Length:260 Identity:70/260 - (26%)
Similarity:114/260 - (43%) Gaps:66/260 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly   137 VHIDVGGTIYTSSLETLTKYPESKLAKLFNGQIPIVLDS---LK----QHYFIDRDGGMFRHILN 194
            |.:||||||:.:|..||||         |||.:.|:|:|   ||    ...||||....|..|||
 Worm     5 VQLDVGGTIFKTSKSTLTK---------FNGFLKIMLESDIGLKIDESGSIFIDRSPKHFDLILN 60

  Fly   195 FMRNSRLLIAEDFPDLEL----LLEEARYYEVEPMIKQLESMRKDRVRNGNYLVAPPTPPARHIK 255
            |||:..:::    |..||    ||.||::|.::.:| :|.|::.:.|:       .|....|.|:
 Worm    61 FMRDGDVVL----PSCELTVKELLAEAQFYLLDELI-ELCSLKIEPVQ-------APKIKLRFIE 113

  Fly   256 TSPRTSASPECNYEVVALHISPDL-GERIMLSAERAL----------------LDELFPEASQAT 303
            ...:.       .:::|....|.| .|..|:..:.::                .|..|...|:..
 Worm   114 NDSQL-------LQILAAQQKPMLIIEYCMVGNDMSIPYNFNLYEFIEKQSHQFDIYFQRLSEDE 171

  Fly   304 QSS--RSGVSWNQGDWGQIIRFPLNGYCKLNSVQVLTRLLNAGF--TIEASVGGQQFSEYLLARR 364
            .|.  ::.:.|...:.|...:||.|  .::|....:.|  :|.|  .:|..:|  :|.|:|..:|
 Worm   172 SSHKWKARIKWKPTENGYYSQFPYN--LRINRGGRIIR--DAVFLERLEKMIG--EFDEFLKKQR 230

  Fly   365  364
             Worm   231  230

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
twzNP_001246449.1 BTB_POZ_KCTD1-like 137..230 CDD:349670 40/103 (39%)
F22E5.8NP_001364741.1 BTB_2 5..95 CDD:396684 40/103 (39%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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